Name:
Osmic Acid Anhydride
Synonym:
Osmic acid; Osmium tetroxide; Perosmic oxide
CAS:
20816-12-0
Section 1 - Chemical Product
MSDS Name:Osmic Acid Anhydride
Synonym:Osmic acid; Osmium tetroxide; Perosmic oxide
Synonym:Osmic acid; Osmium tetroxide; Perosmic oxide
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 20816-12-0 | OSMIUM TETROXIDE | 100 | 244-058-7 |
| Hazard Symbols: T+ C Risk Phrases: 26/27/28 34 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. May result in corneal injury. May cause blindness.
Skin:
Causes skin burns.
Ingestion:
Aspiration hazard. Causes gastrointestinal tract burns. May cause kidney damage. Causes cough, sore throat, chest pain, and lightheadedness.
Inhalation:
Causes chemical burns to the respiratory tract. May cause bronchopneumonia and possible death.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated exposure may cause adverse reproductive effects.
Very toxic by inhalation, in contact with skin and if swallowed.
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. May result in corneal injury. May cause blindness.
Skin:
Causes skin burns.
Ingestion:
Aspiration hazard. Causes gastrointestinal tract burns. May cause kidney damage. Causes cough, sore throat, chest pain, and lightheadedness.
Inhalation:
Causes chemical burns to the respiratory tract. May cause bronchopneumonia and possible death.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated exposure may cause adverse reproductive effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
Evacuate area and fight fire from a safe distance. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Oxidizer. Greatly increases the burning rate of combustible materials. Containers may explode in the heat of a fire. Contact with metals may evolve flammable hydrogen gas.
Extinguishing Media:
Do NOT get water inside containers. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Evacuate area and fight fire from a safe distance. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Oxidizer. Greatly increases the burning rate of combustible materials. Containers may explode in the heat of a fire. Contact with metals may evolve flammable hydrogen gas.
Extinguishing Media:
Do NOT get water inside containers. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Reduce airborne dust and prevent scattering by moistening with water. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.
Spills/Leaks:
Reduce airborne dust and prevent scattering by moistening with water. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale.
Storage:
Do not store near combustible materials. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal containers.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale.
Storage:
Do not store near combustible materials. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal containers.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 20816-12-0: United Kingdom, WEL - TWA: 0.0002 ppm TWA (as Os); 0.002 mg/m3 TW (as Os) United Kingdom, WEL - STEL: 0.0006 ppm STEL (as Os); 0.006 mg/m3 (as Os) United States OSHA: 0.002 mg/m3 TWA (As Os) Belgium - TWA: 0.0002 ppm VLE (as Os); 0.0016 mg/m3 VLE (as Os) Belgium - STEL: 0.0006 ppm VLE (as Os); 0.0048 mg/m3 VLE (as Os) France - VME: 0.0002 ppm VME (as Os); 0.002 mg/m3 VME (as Os) Germany: 0.0002 ppm TWA; 0.0021 mg/m3 TWA Germany: Skin absorber Malaysia: 0.0002 ppm TWA (as Os); 0.0016 mg/m3 TWA (as Os) Netherlands: 0.0002 ppm MAC; 0.002 mg/m3 MAC (as Os) Spain: 0.0002 ppm VLA-ED (as Os); 0.002 mg/m3 VLA-ED (as Os) Spain: 0.0006 ppm VLA-EC (as Os); 0.006 mg/m3 VLA-EC (as Os) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 20816-12-0: United Kingdom, WEL - TWA: 0.0002 ppm TWA (as Os); 0.002 mg/m3 TW (as Os) United Kingdom, WEL - STEL: 0.0006 ppm STEL (as Os); 0.006 mg/m3 (as Os) United States OSHA: 0.002 mg/m3 TWA (As Os) Belgium - TWA: 0.0002 ppm VLE (as Os); 0.0016 mg/m3 VLE (as Os) Belgium - STEL: 0.0006 ppm VLE (as Os); 0.0048 mg/m3 VLE (as Os) France - VME: 0.0002 ppm VME (as Os); 0.002 mg/m3 VME (as Os) Germany: 0.0002 ppm TWA; 0.0021 mg/m3 TWA Germany: Skin absorber Malaysia: 0.0002 ppm TWA (as Os); 0.0016 mg/m3 TWA (as Os) Netherlands: 0.0002 ppm MAC; 0.002 mg/m3 MAC (as Os) Spain: 0.0002 ppm VLA-ED (as Os); 0.002 mg/m3 VLA-ED (as Os) Spain: 0.0006 ppm VLA-EC (as Os); 0.006 mg/m3 VLA-EC (as Os) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: white to pale yellow
Odor: chlorine-like
pH: Not available.
Vapor Pressure: 7 mm Hg @ 20C
Viscosity: Not available.
Boiling Point: 130 deg C @ 760.00mmHg
Freezing/Melting Point: 39.50 - 41.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water: 7.24g/100ml (25 c)
Specific Gravity/Density: 4.9
Molecular Formula: O4Os
Molecular Weight: 254.20
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, acids, metals, excess heat, bases.
Incompatibilities with Other Materials:
Combustible materials, Hydrogen chloride, Reducing agents, Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, acids, metals, excess heat, bases.
Incompatibilities with Other Materials:
Combustible materials, Hydrogen chloride, Reducing agents, Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 20816-12-0: RN1140000 LD50/LC50:
CAS# 20816-12-0: Oral, mouse: LD50 = 162 mg/kg.
Carcinogenicity:
OSMIUM TETROXIDE - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 20816-12-0: RN1140000 LD50/LC50:
CAS# 20816-12-0: Oral, mouse: LD50 = 162 mg/kg.
Carcinogenicity:
OSMIUM TETROXIDE - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: OSMIUM TETROXIDE
Hazard Class: 6.1
UN Number: 2471
Packing Group: I
IMO
Shipping Name: OSMIUM TETROXIDE
Hazard Class: 6.1
UN Number: 2471
Packing Group: I
RID/ADR
Shipping Name: OSMIUM TETROXIDE
Hazard Class: 6.1
UN Number: 2471
Packing group: I
USA RQ: CAS# 20816-12-0: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ C
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 34 Causes burns.
Safety Phrases:
S 1/2 Keep locked up and out of reach of children.
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 20816-12-0: 2
Canada
CAS# 20816-12-0 is listed on Canadas DSL List.
CAS# 20816-12-0 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 20816-12-0 is listed on the TSCA inventory.
