Name:
Oxalic acid dihydrate 99+%
Synonym:
Ethanedioic acid dihydrate
CAS:
144-62-7
Section 1 - Chemical Product
MSDS Name:Oxalic acid dihydrate 99+%
Synonym:Ethanedioic acid dihydrate
Synonym:Ethanedioic acid dihydrate
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 144-62-7 | Oxalic acid, anhydrous | - | 205-634-3 |
| Hazard Symbols: XN Risk Phrases: 21/22 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful in contact with skin and if swallowed.
Potential Health Effects
Eye:
May cause severe eye irritation. May result in corneal injury.
Skin:
Causes skin irritation. Harmful if absorbed through the skin. Rare chemical burns may occur from oxalic acid and may cause hypocalcemia.
Gangrene has occurred in the hands of people working with oxalic acid solutions without rubber gloves. The skin lesions are characterized by cracking of the skin and the development of slow-healing ulcers.
The skin may be bluish in color, and the nails brittle and yellow.
Ingestion:
Oxalic acid is toxic because of its acidic and chelating properties.
It is especially toxic when ingested. As little as 5 grams (71 mg/kg) may be fatal. Ulcerations of the mouth, vomiting of blood, and rapid appearance of shock, convulsions, twitching, tetany, and cardiovascular collapse may occur following ingestion of oxalic acid or its soluble salts. Oxalic acid can bind calcium to form calcium oxalate which is insoluble at physiological pH. Calcium oxalate thus formed might precipitate in the kidney tubules and the brain.
Hypocalcemia secondary to calcium oxalate formation might disturb the function of the heart and nerves.
Inhalation:
Inhalation of oxalic acid produces irritation of the respiratory tract, ulceration of the mucous membranes, headaches, nervousness, cough, vomiting, emaciation, back pain (due to kidney injury), and weakness.
Chronic:
Inhalation of oxalic acid dust or mist over a long period of time might result in weight loss and respiratory tract inflammation. Rats administered oxalic acid at 2.5 and 5% in the diet for 70 days developed depressed thyroid function and weight loss. A study of railroad car cleaners in Norway who were heavily exposed to oxalic acid solutions and vapors revealed a 53% prevalence of urolithiasis (the formation of urinary stones), compared to a rate of 12% among unexposed workers from the same company.
Harmful in contact with skin and if swallowed.
Potential Health Effects
Eye:
May cause severe eye irritation. May result in corneal injury.
Skin:
Causes skin irritation. Harmful if absorbed through the skin. Rare chemical burns may occur from oxalic acid and may cause hypocalcemia.
Gangrene has occurred in the hands of people working with oxalic acid solutions without rubber gloves. The skin lesions are characterized by cracking of the skin and the development of slow-healing ulcers.
The skin may be bluish in color, and the nails brittle and yellow.
Ingestion:
Oxalic acid is toxic because of its acidic and chelating properties.
It is especially toxic when ingested. As little as 5 grams (71 mg/kg) may be fatal. Ulcerations of the mouth, vomiting of blood, and rapid appearance of shock, convulsions, twitching, tetany, and cardiovascular collapse may occur following ingestion of oxalic acid or its soluble salts. Oxalic acid can bind calcium to form calcium oxalate which is insoluble at physiological pH. Calcium oxalate thus formed might precipitate in the kidney tubules and the brain.
Hypocalcemia secondary to calcium oxalate formation might disturb the function of the heart and nerves.
Inhalation:
Inhalation of oxalic acid produces irritation of the respiratory tract, ulceration of the mucous membranes, headaches, nervousness, cough, vomiting, emaciation, back pain (due to kidney injury), and weakness.
Chronic:
Inhalation of oxalic acid dust or mist over a long period of time might result in weight loss and respiratory tract inflammation. Rats administered oxalic acid at 2.5 and 5% in the diet for 70 days developed depressed thyroid function and weight loss. A study of railroad car cleaners in Norway who were heavily exposed to oxalic acid solutions and vapors revealed a 53% prevalence of urolithiasis (the formation of urinary stones), compared to a rate of 12% among unexposed workers from the same company.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Antidote: Intravenous administration of calcium gluconate or calcium chloride may be required if hypocalcemia or hypocalcemic tetany occur.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Antidote: Intravenous administration of calcium gluconate or calcium chloride may be required if hypocalcemia or hypocalcemic tetany occur.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Discard contaminated shoes. Use only with adequate ventilation.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Discard contaminated shoes. Use only with adequate ventilation.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Powder
Appearance: white
Odor: odorless
pH: Not available.
Vapor Pressure: .92 mm Hg @ 60 deg C
Viscosity: Not available.
Boiling Point: Not applicable.
Freezing/Melting Point: 102 deg C sublimes
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Moderately Soluble.
Specific Gravity/Density: 1.90
Molecular Formula: C2H2O4.2H2O
Molecular Weight: 126.04
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, metals.
Incompatibilities with Other Materials:
Strong oxidizing agents, hypochlorite, silver, strong alkalies, chlorites, furfuryl alcohol.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, acrid smoke and fumes, formic acid.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, metals.
Incompatibilities with Other Materials:
Strong oxidizing agents, hypochlorite, silver, strong alkalies, chlorites, furfuryl alcohol.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, acrid smoke and fumes, formic acid.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 144-62-7: RO2450000 CAS# 6153-56-6 unlisted.
LD50/LC50:
CAS# 144-62-7: Draize test, rabbit, eye: 250 ug/24H Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Oral, rat: LD50 = 7500 mg/kg.
CAS# 6153-56-6.
Carcinogenicity:
Oxalic acid, anhydrous - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Oxalic acid dihydrate - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
CAS# 144-62-7: RO2450000 CAS# 6153-56-6 unlisted.
LD50/LC50:
CAS# 144-62-7: Draize test, rabbit, eye: 250 ug/24H Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Oral, rat: LD50 = 7500 mg/kg.
CAS# 6153-56-6.
Carcinogenicity:
Oxalic acid, anhydrous - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Oxalic acid dihydrate - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Bluegill/Sunfish: LC50 = 4000 mg/L; 24 Hr.; Static ConditionsFish: Mosquito Fish: LC50 = 1350 mg/L; 24 Hr.; Static Conditions
Fish: Bluegill/Sunfish: LC50 = 4000 mg/L; 24 Hr.; Static ConditionsFish: Mosquito Fish: LC50 = 1350 mg/L; 24 Hr.; Static Conditions
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.*
Hazard Class: 8
UN Number: 3261
Packing Group: II
IMO
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3261
Packing Group: II
RID/ADR
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
Dangerous Goods Code: 8(39B)
UN Number: 3261
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 21/22 Harmful in contact with skin and if
swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 144-62-7: 1
CAS# 6153-56-6: 1
United Kingdom Occupational Exposure Limits
CAS# 144-62-7: OES-United Kingdom, TWA 1 mg/m3 TWA
CAS# 144-62-7: OES-United Kingdom, STEL 2 mg/m3 STEL
CAS# 144-62-7: OES-United Kingdom, STEL 2 mg/m3 STEL
Canada
CAS# 144-62-7 is listed on Canadas DSL List.
CAS# 144-62-7 is listed on Canadas Ingredient Disclosure List.
CAS# 6153-56-6 is not listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 144-62-7: OEL-ARAB Republic of Egypt:TWA 1 mg/m3
OEL-AUSTRALIA:TWA 1 mg/m3;STEL 2 mg/m3
OEL-BELGIUM:TWA 1 mg/m3;STEL 2 mg/m3
OEL-DENMARK:TWA 1 mg/m3
OEL-FINLAND:TWA 1 mg/m3;STEL 3 mg/m3
OEL-FRANCE:TWA 1 mg/m3
OEL-THE NETHERLANDS:TWA 1 mg/m3
OEL-THE PHILIPPINES:TWA 1 mg/m3
OEL-SWITZERLAND:TWA 1 mg/m3
OEL-UNITED KINGDOM:TWA 1 mg/m3;STEL 2 mg/m3
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 144-62-7 is listed on the TSCA inventory.
CAS# 6153-56-6 is not on the TSCA Inventory. It is a hydrate and
exempt from TSCA Inventory requirements (40CFR720.3(u)(2)).
