Name:
p-Toluenesulfonyl chloride
Synonym:
Toluene-4-sulfonyl chloride; Tosyl chloride
CAS:
98-59-9
Section 1 - Chemical Product
MSDS Name:p-Toluenesulfonyl chloride
Synonym:Toluene-4-sulfonyl chloride; Tosyl chloride
Synonym:Toluene-4-sulfonyl chloride; Tosyl chloride
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 98-59-9 | p-Toluenesulfonyl chloride | >99 | 202-684-8 |
| Hazard Symbols: C Risk Phrases: 29 34 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Contact with water liberates toxic gas. Causes burns.
Potential Health Effects
Eye:
Causes eye burns. Lachrymator (substance which increases the flow of tears).
Skin:
Causes skin burns. This material is a vesicant, that is, it will induce blistering.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract.
Chronic:
Chronic exposure may cause effects similar to those of acute exposure. Repeated exposure to low concentrations of HCl vapor or mist may cause bleeding of nose and gums. Chronic bronchitis and gastritis have also been reported.
Contact with water liberates toxic gas. Causes burns.
Potential Health Effects
Eye:
Causes eye burns. Lachrymator (substance which increases the flow of tears).
Skin:
Causes skin burns. This material is a vesicant, that is, it will induce blistering.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract.
Chronic:
Chronic exposure may cause effects similar to those of acute exposure. Repeated exposure to low concentrations of HCl vapor or mist may cause bleeding of nose and gums. Chronic bronchitis and gastritis have also been reported.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion.
Extinguishing Media:
Use carbon dioxide or dry chemical. DO NOT USE WATER OR FOAM.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion.
Extinguishing Media:
Use carbon dioxide or dry chemical. DO NOT USE WATER OR FOAM.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Do not get water on spilled substances or inside containers.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Do not get water on spilled substances or inside containers.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Do not allow contact with water.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Corrosives area. Do not store in metal containers.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Do not allow contact with water.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Corrosives area. Do not store in metal containers.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 98-59-9: United Kingdom, WEL - STEL: 5 mg/m3 STEL Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 98-59-9: United Kingdom, WEL - STEL: 5 mg/m3 STEL Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystalline powder
Color: white
Odor: characteristic odor
pH: Not available.
Vapor Pressure: 0.5 mm Hg @ 75 deg C
Viscosity: Not available.
Boiling Point: 146 deg C @ 15 mmHg
Freezing/Melting Point: 67 deg C
Autoignition Temperature: Not available.
Flash Point: 128 deg C ( 262.40 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 220 deg C
Solubility in water: Reacts.
Specific Gravity/Density: 1.49 g/cm3
Molecular Formula: C7H7ClO2S
Molecular Weight: 190.64
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Reacts with water to form corresponding acid. Material hydrolyzes in contact with moisture/water releasing toxic and corrosive fumes of hydrogen chloride and aqueous hydrochloric acid.
Conditions to Avoid:
Dust generation, contact with water.
Incompatibilities with Other Materials:
Water, strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures. Reacts with water to form corresponding acid. Material hydrolyzes in contact with moisture/water releasing toxic and corrosive fumes of hydrogen chloride and aqueous hydrochloric acid.
Conditions to Avoid:
Dust generation, contact with water.
Incompatibilities with Other Materials:
Water, strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 98-59-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
p-Toluenesulfonyl chloride - Not listed by ACGIH, IARC, or NTP.
CAS# 98-59-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
p-Toluenesulfonyl chloride - Not listed by ACGIH, IARC, or NTP.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (P-TOLUEN
ESULFONYLCHLORIDE)
Hazard Class: 8
UN Number: 3261
Packing Group: II
IMO
Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S., (P-TOLUE
NESULFONYL CHLORIDE)
Hazard Class: 8
UN Number: 3261
Packing Group: II
RID/ADR
Shipping Name: CORROSIVE SOLID, N.O.S.
Hazard Class: 8
UN Number: 1759
Packing group: II
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 29 Contact with water liberates toxic gas.
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 98-59-9: 1
Canada
CAS# 98-59-9 is listed on Canadas DSL List.
CAS# 98-59-9 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 98-59-9 is listed on the TSCA inventory.
