Name:
p-Toluidine
Synonym:
4-Aminotoluene, 4-Methylanilin
CAS:
106-49-0
Section 1 - Chemical Product
MSDS Name:p-Toluidine
Synonym:4-Aminotoluene, 4-Methylanilin
Synonym:4-Aminotoluene, 4-Methylanilin
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 106-49-0 | p-Toluidine | 96 | 203-403-1 |
| Hazard Symbols: T N Risk Phrases: 23/24/25 33 50 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. Danger of cumulative effects. Very toxic to aquatic organisms.
Potential Health Effects
The toxicological properties of this material have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation.
Toxic by inhalation, in contact with skin and if swallowed. Danger of cumulative effects. Very toxic to aquatic organisms.
Potential Health Effects
The toxicological properties of this material have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal.
Section 7 - HANDLING and STORAGE
Handling:
Not available.
Storage:
Keep refrigerated. (Store below 4C/39F.)
Not available.
Storage:
Keep refrigerated. (Store below 4C/39F.)
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 106-49-0: Belgium - TWA: 2 ppm VLE; 8.9 mg/m3 VLE Germany: 0.2 ppm TWA; 1 mg/m3 TWA Germany: Skin absorber Malaysia: 2 ppm TWA; 8.8 mg/m3 TWA Netherlands: 2 ppm MAC; 9 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 2 ppm VLA-ED; 8.9 mg/m3 VLA-ED Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 106-49-0: Belgium - TWA: 2 ppm VLE; 8.9 mg/m3 VLE Germany: 0.2 ppm TWA; 1 mg/m3 TWA Germany: Skin absorber Malaysia: 2 ppm TWA; 8.8 mg/m3 TWA Netherlands: 2 ppm MAC; 9 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 2 ppm VLA-ED; 8.9 mg/m3 VLA-ED Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Not available.
Color: Not available.
Odor: None reported.
pH: Not available.
Vapor Pressure: 1.3 mbar @ 43 C
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 0 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.0500g/cm3
Molecular Formula: CH3C6H4NH2
Molecular Weight: 107.16
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Not available.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Not available.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 106-49-0: XU3150000 LD50/LC50:
CAS# 106-49-0: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >640 mg/m3/1H; Oral, mouse: LD50 = 330 mg/kg; Oral, rabbit: LD50 = 270 mg/kg; Oral, rat: LD50 = 336 mg/kg; Skin, rabbit: LD50 = 890 mg/kg.
Carcinogenicity:
p-Toluidine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Other:
See actual entry in RTECS for complete information.
CAS# 106-49-0: XU3150000 LD50/LC50:
CAS# 106-49-0: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >640 mg/m3/1H; Oral, mouse: LD50 = 330 mg/kg; Oral, rabbit: LD50 = 270 mg/kg; Oral, rat: LD50 = 336 mg/kg; Skin, rabbit: LD50 = 890 mg/kg.
Carcinogenicity:
p-Toluidine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: TOLUIDINE
Hazard Class: 6.1
UN Number: 1708
Packing Group: II
IMO
Shipping Name: TOLUIDINE
Hazard Class: 6.1
UN Number: 1708
Packing Group: II
RID/ADR
Shipping Name: TOLUIDINE
Hazard Class: 6.1
UN Number: 1708
Packing group:
USA RQ: CAS# 106-49-0: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 33 Danger of cumulative effects.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 106-49-0: 2
Canada
CAS# 106-49-0 is listed on Canadas DSL List.
CAS# 106-49-0 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 106-49-0 is listed on the TSCA inventory.
