Name:
PBS Phosphate Buffered Saline
Synonym:
None
CAS:
7447-40-7
Section 1 - Chemical Product
MSDS Name:PBS Phosphate Buffered Saline
Synonym:None
Synonym:None
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 7447-40-7 | Potassium chloride | ~2.0 | 231-211-8 |
| Hazard Symbols: None Listed. Risk Phrases: None Listed. |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
May cause skin irritation.
Ingestion:
Ingestion of large amounts may cause gastrointestinal irritation.
May cause gastric disturbances and electrolytic imbalance.
Inhalation:
Inhalation of dust may cause respiratory tract irritation.
Chronic:
No information found.
Not available.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
May cause skin irritation.
Ingestion:
Ingestion of large amounts may cause gastrointestinal irritation.
May cause gastric disturbances and electrolytic imbalance.
Inhalation:
Inhalation of dust may cause respiratory tract irritation.
Chronic:
No information found.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance is noncombustible.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance is noncombustible.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7447-40-7: Russia: 5 mg/m3 TWA CAS# 7558-79-4: CAS# 7647-14-5: Russia: 5 mg/m3 TWA CAS# 7778-77-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7447-40-7: Russia: 5 mg/m3 TWA CAS# 7558-79-4: CAS# 7647-14-5: Russia: 5 mg/m3 TWA CAS# 7778-77-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density:
Molecular Formula: Mixture
Molecular Weight: 0
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Potassium chloride is incompatible with potassium permanganate.
Sodium chloride is incompatible with dichloromaleic anhydride + urea, lithium, and nitrogen compounds. Potassium phosphate dibasic and monobasic may react violently with strong acids.
Hazardous Decomposition Products:
Oxides of phosphorus, sodium oxide, oxides of potassium.
Hazardous Polymerization: Will not occur.
Stable.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Potassium chloride is incompatible with potassium permanganate.
Sodium chloride is incompatible with dichloromaleic anhydride + urea, lithium, and nitrogen compounds. Potassium phosphate dibasic and monobasic may react violently with strong acids.
Hazardous Decomposition Products:
Oxides of phosphorus, sodium oxide, oxides of potassium.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7447-40-7: TS8050000 CAS# 7558-79-4: WC4500000 CAS# 7647-14-5: VZ4725000 CAS# 7778-77-0: TC6615500 LD50/LC50:
CAS# 7447-40-7: Draize test, rabbit, eye: 500 mg/24H Mild; Oral, mouse: LD50 = 1500 mg/kg; Oral, rat: LD50 = 2600 mg/kg.
CAS# 7558-79-4: Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Oral, rat: LD50 = 17 gm/kg.
CAS# 7647-14-5: Draize test, rabbit, eye: 100 mg Mild; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, skin: 50 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >42 gm/m3/1H; Oral, mouse: LD50 = 4 gm/kg; Oral, rat: LD50 = 3000 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
CAS# 7778-77-0: Skin, rabbit: LD50 = >4640 mg/kg.
Carcinogenicity:
Potassium chloride - Not listed by ACGIH, IARC, or NTP.
Sodium phosphate, dibasic - Not listed by ACGIH, IARC, or NTP.
Sodium Chloride - Not listed by ACGIH, IARC, or NTP.
Potassium phosphate, Monobasic - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 7447-40-7: TS8050000 CAS# 7558-79-4: WC4500000 CAS# 7647-14-5: VZ4725000 CAS# 7778-77-0: TC6615500 LD50/LC50:
CAS# 7447-40-7: Draize test, rabbit, eye: 500 mg/24H Mild; Oral, mouse: LD50 = 1500 mg/kg; Oral, rat: LD50 = 2600 mg/kg.
CAS# 7558-79-4: Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Oral, rat: LD50 = 17 gm/kg.
CAS# 7647-14-5: Draize test, rabbit, eye: 100 mg Mild; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, skin: 50 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >42 gm/m3/1H; Oral, mouse: LD50 = 4 gm/kg; Oral, rat: LD50 = 3000 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
CAS# 7778-77-0: Skin, rabbit: LD50 = >4640 mg/kg.
Carcinogenicity:
Potassium chloride - Not listed by ACGIH, IARC, or NTP.
Sodium phosphate, dibasic - Not listed by ACGIH, IARC, or NTP.
Sodium Chloride - Not listed by ACGIH, IARC, or NTP.
Potassium phosphate, Monobasic - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 7558-79-4: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 7447-40-7: 1
CAS# 7558-79-4: 1
CAS# 7647-14-5: 0
CAS# 7778-77-0: 1
Canada
CAS# 7447-40-7 is listed on Canadas DSL List.
CAS# 7558-79-4 is listed on Canadas DSL List.
CAS# 7647-14-5 is listed on Canadas DSL List.
CAS# 7778-77-0 is listed on Canadas DSL List.
CAS# 7447-40-7 is not listed on Canadas Ingredient Disclosure List.
CAS# 7558-79-4 is not listed on Canadas Ingredient Disclosure List.
CAS# 7647-14-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 7778-77-0 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7447-40-7 is listed on the TSCA inventory.
CAS# 7558-79-4 is listed on the TSCA inventory.
CAS# 7647-14-5 is listed on the TSCA inventory.
CAS# 7778-77-0 is listed on the TSCA inventory.
