Name:
Pentachlorophenol
Synonym:
PCP; 1-Hydroxypentachlorobenzene; 2,3,4,5,6-Pentachlorophenol
CAS:
87-86-5
Section 1 - Chemical Product
MSDS Name:Pentachlorophenol
Synonym:PCP; 1-Hydroxypentachlorobenzene; 2,3,4,5,6-Pentachlorophenol
Synonym:PCP; 1-Hydroxypentachlorobenzene; 2,3,4,5,6-Pentachlorophenol
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 87-86-5 | Pentachlorophenol | >86 | 201-778-6 |
| Hazard Symbols: T N Risk Phrases: 26 36/37/38 40 24/25 50/53 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Very toxic by inhalation. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. Toxic in contact with skin and if swallowed. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Possible risks of irreversible effects.Dangerous for the environment.
Potential Health Effects
Eye:
Causes eye irritation and possible burns. May cause visual damage, inflammation of the conjunctiva, corneal opacity and slight physiologic dilatation of the pupil.
Skin:
May be fatal if absorbed through the skin. Substance is rapidly absorbed through the skin. Causes symptoms similar to those of inhalation. Causes skin irritation and possible burns.
Ingestion:
May be fatal if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause effects similar to those of acute inhalation.
Inhalation:
May be fatal if inhaled. May cause increased perspiration, increased temperature, increased heart rate, increased breathing, weakness, nausea, vomiting, abdominal pain, headache, Systemic intoxication is cumulative and has been fatal. May cause violent sneezing and coughing. Inhalation may cause damage to the circulatory system and heart and possible death due to cardiac failure. Causes irritation of the mucous membrane and upper respiratory tract.
Chronic:
Possible cancer hazard based on tests with laboratory animals. May cause liver and kidney damage. Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Chronic exposure has resulted in an increased prevalence of conjunctivitis, sinsuitis, bronchitis, polyneuritis, and dermatitis.
Exposure may cause blood effects and bone marrow damage. Chronic exposure may cause lung damage. Laboratory experiments have resulted in mutagenic effects.
Very toxic by inhalation. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. Toxic in contact with skin and if swallowed. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Possible risks of irreversible effects.Dangerous for the environment.
Potential Health Effects
Eye:
Causes eye irritation and possible burns. May cause visual damage, inflammation of the conjunctiva, corneal opacity and slight physiologic dilatation of the pupil.
Skin:
May be fatal if absorbed through the skin. Substance is rapidly absorbed through the skin. Causes symptoms similar to those of inhalation. Causes skin irritation and possible burns.
Ingestion:
May be fatal if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause effects similar to those of acute inhalation.
Inhalation:
May be fatal if inhaled. May cause increased perspiration, increased temperature, increased heart rate, increased breathing, weakness, nausea, vomiting, abdominal pain, headache, Systemic intoxication is cumulative and has been fatal. May cause violent sneezing and coughing. Inhalation may cause damage to the circulatory system and heart and possible death due to cardiac failure. Causes irritation of the mucous membrane and upper respiratory tract.
Chronic:
Possible cancer hazard based on tests with laboratory animals. May cause liver and kidney damage. Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Chronic exposure has resulted in an increased prevalence of conjunctivitis, sinsuitis, bronchitis, polyneuritis, and dermatitis.
Exposure may cause blood effects and bone marrow damage. Chronic exposure may cause lung damage. Laboratory experiments have resulted in mutagenic effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively. Persons with pre-existing skin disorders or impaired respiratory or pulmonary function may be at increased risk to the effects of this substance. Effects may be delayed.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively. Persons with pre-existing skin disorders or impaired respiratory or pulmonary function may be at increased risk to the effects of this substance. Effects may be delayed.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use extinguishing media most appropriate for the surrounding fire. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use extinguishing media most appropriate for the surrounding fire. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Do not let this chemical enter the environment.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Do not let this chemical enter the environment.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.
Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.
Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 87-86-5: United States OSHA: 0.5 mg/m3 TWA Belgium - TWA: 0.5 mg/m3 VLE France - VME: 0.5 mg/m3 VME Japan: 0.5 mg/m3 OEL Malaysia: 0.5 mg/m3 TWA Netherlands: 0.06 mg/m3 MAC Russia: 0.1 mg/m3 TWA Spain: 0.5 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 87-86-5: United States OSHA: 0.5 mg/m3 TWA Belgium - TWA: 0.5 mg/m3 VLE France - VME: 0.5 mg/m3 VME Japan: 0.5 mg/m3 OEL Malaysia: 0.5 mg/m3 TWA Netherlands: 0.06 mg/m3 MAC Russia: 0.1 mg/m3 TWA Spain: 0.5 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: dark colored
Odor: Benzene like
pH: Not available.
Vapor Pressure: 40 mm Hg @ 211.2 C
Viscosity: Not available.
Boiling Point: 310 deg C @ 760 mmHg
Freezing/Melting Point: 190-191 C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 310 deg C
Solubility in water: slightly soluble
Specific Gravity/Density: 1.9790g/cm3
Molecular Formula: C6HCl5O
Molecular Weight: 266.33
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, acid anhydrides, alkalies, acid chlorides, organic materials.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, chlorinated phenols.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, acid anhydrides, alkalies, acid chlorides, organic materials.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, chlorinated phenols.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 87-86-5: SM6300000 SM6314000 SM6321000 LD50/LC50:
CAS# 87-86-5: Draize test, rabbit, eye: 100 uL/24H Mild; Inhalation, mouse: LC50 = 225 mg/m3; Inhalation, mouse: LC50 = 225 mg/m3; Inhalation, rat: LC50 = 355 mg/m3; Inhalation, rat: LC50 = 200 mg/m3; Inhalation, rat: LC50 = 335 mg/m3; Oral, mouse: LD50 = 36 mg/kg; Oral, mouse: LD50 = 117 mg/kg; Oral, mouse: LD50 = 30 mg/kg; Oral, rabbit: LD50 = 200 mg/kg; Oral, rat: LD50 = 27 mg/kg; Oral, rat: LD50 = 27 mg/kg; Oral, rat: LD50 = 50 mg/kg; Skin, rat: LD50 = 96 mg/kg; Skin, rat: LD50 = 26 mg/kg.
Carcinogenicity:
Pentachlorophenol - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/90 Other:
See actual entry in RTECS for complete information.
CAS# 87-86-5: SM6300000 SM6314000 SM6321000 LD50/LC50:
CAS# 87-86-5: Draize test, rabbit, eye: 100 uL/24H Mild; Inhalation, mouse: LC50 = 225 mg/m3; Inhalation, mouse: LC50 = 225 mg/m3; Inhalation, rat: LC50 = 355 mg/m3; Inhalation, rat: LC50 = 200 mg/m3; Inhalation, rat: LC50 = 335 mg/m3; Oral, mouse: LD50 = 36 mg/kg; Oral, mouse: LD50 = 117 mg/kg; Oral, mouse: LD50 = 30 mg/kg; Oral, rabbit: LD50 = 200 mg/kg; Oral, rat: LD50 = 27 mg/kg; Oral, rat: LD50 = 27 mg/kg; Oral, rat: LD50 = 50 mg/kg; Skin, rat: LD50 = 96 mg/kg; Skin, rat: LD50 = 26 mg/kg.
Carcinogenicity:
Pentachlorophenol - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/90 Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Rainbow trout: LC50 = 0.052 mg/L; 96 Hr; Static bioassay at 11C (pH 7.2-7.5)Fish: Fathead Minnow: LC50 = 0.205 mg/L; 96 Hr; Static bioassay at 20C (pH 7.2-7.5)Fish: Bluegill/Sunfish: LC50 = 0.032 mg/L; 96 Hr; Static bioassay at 15C (pH 7.2-7.5)Bacteria: Phytobacterium phosphoreum: EC50 = 0.519 mg/L; 30 min; Microtox testAlgae: Green algae: EC50 = 0.09 mg/L; 96 Hr; UnspecifiedIn soil, pentachlorophenol will slowly biodegrade and leaching into ground water is expected. When released into water it adsorbs considerably to sediment, photodegrades (especially at higher pHs) and slowly biodegrades. Pentachlorophenol is expected to moderately Other Harmful to aquatic life in very low concentrations.
Fish: Rainbow trout: LC50 = 0.052 mg/L; 96 Hr; Static bioassay at 11C (pH 7.2-7.5)Fish: Fathead Minnow: LC50 = 0.205 mg/L; 96 Hr; Static bioassay at 20C (pH 7.2-7.5)Fish: Bluegill/Sunfish: LC50 = 0.032 mg/L; 96 Hr; Static bioassay at 15C (pH 7.2-7.5)Bacteria: Phytobacterium phosphoreum: EC50 = 0.519 mg/L; 30 min; Microtox testAlgae: Green algae: EC50 = 0.09 mg/L; 96 Hr; UnspecifiedIn soil, pentachlorophenol will slowly biodegrade and leaching into ground water is expected. When released into water it adsorbs considerably to sediment, photodegrades (especially at higher pHs) and slowly biodegrades. Pentachlorophenol is expected to moderately Other Harmful to aquatic life in very low concentrations.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: PENTACHLOROPHENOL
Hazard Class: 6.1
UN Number: 3155
Packing Group: II
IMO
Shipping Name: PENTACHLOROPHENOL
Hazard Class: 6.1
UN Number: 3155
Packing Group: II
RID/ADR
Shipping Name: PENTACHLOROPHENOL
Hazard Class: 6.1
UN Number: 3155
Packing group: II
USA RQ: CAS# 87-86-5: 10 lb final RQ; 4.54 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 24/25 Toxic in contact with skin and if swallowed.
R 26 Very toxic by inhalation.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 40 Limited evidence of a carcinogenic effect.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 22 Do not breathe dust.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 52 Not recommended for interior use on large
surface areas.
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 87-86-5: 3
Canada
CAS# 87-86-5 is listed on Canadas DSL List.
CAS# 87-86-5 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 87-86-5 is listed on the TSCA inventory.
