MSDS Name:Phenol / Chloroform / Isoamyl alcohol mixture (25:24:1)
Synonym:None Known

EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. Causes burns. Limited evidence of a carcinogenic effect. Harmful : danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed.Light sensitive.Mutagen.
Potential Health Effects
Eye:
Causes eye burns. Causes redness and pain.
Skin:
May be fatal if absorbed through the skin. Causes skin burns. Phenol solutions may be absorbed through the skin rapidly to produce systemic poisoning and possible death.
Ingestion:
May be fatal if swallowed. Causes gastrointestinal tract burns. May cause liver damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
May cause cardiac disturbances. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. Possible aspiration hazard. May cause hallucinations and distorted perceptions.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May be fatal if exposed to high concentrations. May cause cardiac sensitization and possible failure. Causes chemical burns to the respiratory tract. Inhalation of large amounts may cause respiratory stimulation, followed by respiratory depression, convulsions and possible death due to respiratory paralysis. May be absorbed through the lungs.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated skin contact may cause defatting and dermatitis. May cause reproductive and fetal effects. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects.
Repeated skin contact may cause dermatitis with dark pigmentation of the skin. Toxicity may be increased by exposure to alcohol, steroids, and ketones. Prolonged exposure may cause liver, kidney, and heart damage.

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Causes cardiac sensitization to endogenous catelcholamines which may lead to cardiac arrhythmias. Do NOT use adrenergic agents such as epinephrine or pseudoepinephrine. Persons with liver, kidney, or central nervous system diseases may be at increased risk from exposure to this product. Alcoholic beverage consumption may enhance the toxic effects of this substance. Effects may be delayed.

General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or chemical foam.

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Approach spill from upwind.

Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Do not ingest or inhale.
Store protected from light. Use only in a chemical fume hood.
Storage:
Do not store in direct sunlight. Keep refrigerated. (Store below 4C/39F.) Keep away from acids. Do not store near alkaline substances. Separate from strong mineral acids.

Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 67-66-3: United Kingdom, WEL - TWA: 2 ppm TWA; 9.9 mg/m3 TWA United Kingdom, WEL - STEL: 6 ppm STEL; 29.7 mg/m3 STEL United States OSHA: ; 50 ppm Ceiling; 240 mg/m3 Ceiling Belgium - TWA: 10 ppm VLE; 50 mg/m3 VLE France - VME: 5 ppm VME; 25 mg/m3 VME France - VLE: 50 ppm VLE; 250 mg/m3 VLE Germany: 4 ppm TWA (large technical manufacture and use); 20 mg/m TWA (large technical m Germany: Skin absorber Japan: 10 ppm OEL; 49 mg/m3 OEL Malaysia: 10 ppm TWA; 49 mg/m3 TWA Netherlands: 5 ppm STEL; 25 mg/m3 STEL Netherlands: 1 ppm MAC; 5 mg/m3 MAC Spain: 2 ppm VLA-ED; 10 mg/m3 VLA-ED CAS# 108-95-2: United Kingdom, WEL - TWA: 2 ppm TWA United Kingdom, WEL - STEL: 6 ppm STEL United States OSHA: 5 ppm TWA; 19 mg/m3 TWA Belgium - TWA: 2 ppm VLE; 7.8 mg/m3 VLE France - VME: 5 ppm VME; 19 mg/m3 VME Germany: 5 ppm TWA; 19 mg/m3 TWA Germany: Skin absorber Japan: 5 ppm OEL; 19 mg/m3 OEL Malaysia: 5 ppm TWA; 15 mg/m3 TWA Netherlands: 2 ppm MAC; 8 mg/m3 MAC Russia: 0.3 mg/m3 TWA Spain: 2 ppm VLA-ED; 8 mg/m3 VLA-ED CAS# 123-51-3: United Kingdom, WEL - TWA: 100 ppm TWA; 366 mg/m3 TWA United Kingdom, WEL - STEL: 125 ppm STEL; 458 mg/m3 STEL United States OSHA: 100 ppm TWA; 360 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 366 mg/m3 VLE Belgium - STEL: 125 ppm VLE; 459 mg/m3 VLE France - VME: 100 ppm VME; 360 mg/m3 VME Germany: 100 ppm TWA; 370 mg/m3 TWA Japan: 100 ppm OEL; 360 mg/m3 OEL Malaysia: 100 ppm TWA; 361 mg/m3 TWA Netherlands: 100 ppm MAC; 360 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 100 ppm VLA-ED; 366 mg/m3 VLA-ED Spain: 125 ppm VLA-EC; 458 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Physical State: Liquid
Color: Clear yellow solution
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: Solution
Molecular Weight: 0

Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. Air sensitive. Light sensitive.
Conditions to Avoid:
High temperatures, light, exposure to air.
Incompatibilities with Other Materials:
Alkali metals, fluorine, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), dinitrogen tetraoxide, sodium hydroxide + methanol, potassium tert-butoxide, chemically active metals, powdered aluminum, nitrogen tetroxide, powdered magnesium, acetone + alkali, disilane, perchloric acid + phosphorus pentoxide, sodium methylate, triisopropylphosphine.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, chlorine, phosgene gas.
Hazardous Polymerization: Will not occur.

RTECS#:
CAS# 67-66-3: FS9100000 CAS# 108-95-2: SJ3325000 CAS# 123-51-3: EL5425000 LD50/LC50:
CAS# 67-66-3: Draize test, rabbit, eye: 148 mg; Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 17200 mg/m3/2H; Inhalation, mouse: LC50 = 6000 mg/m3/6H; Inhalation, rat: LC50 = 47702 mg/m3/4H; Inhalation, rat: LC50 = 6000 mg/m3/6H; Oral, mouse: LD50 = 36 mg/kg; Oral, rat: LD50 = 695 mg/kg; Oral, rat: LD50 = 1250 mg/kg; Skin, rabbit: LD50 = >20 gm/kg.
CAS# 108-95-2: Draize test, rabbit, eye: 5 mg Severe; Draize test, rabbit, skin: 500 mg/24H Severe; Draize test, rabbit, skin: 100 mg Mild; Inhalation, mouse: LC50 = 177 mg/m3; Inhalation, mouse: LC50 = 177 mg/m3/4H; Inhalation, rat: LC50 = 316 mg/m3; Inhalation, rat: LC50 = 316 mg/m3/4H; Oral, mouse: LD50 = 270 mg/kg; Oral, rat: LD50 = 317 mg/kg; Oral, rat: LD50 = 512 mg/kg; Skin, rabbit: LD50 = 630 mg/kg; Skin, rat: LD50 = 669 mg/kg; Skin, rat: LD50 = 1500 mg/kg.
CAS# 123-51-3: Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Oral, rabbit: LD50 = 3438 mg/kg; Oral, rat: LD50 = 1300 mg/kg; Oral, rat: LD50 = 4300 mg/kg; Skin, rabbit: LD50 = 3970 uL/kg.
Carcinogenicity:
Chloroform - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 10/1/87 NTP: Suspect carcinogen IARC: Group 2B carcinogen Phenol - Not listed by ACGIH, IARC, or NTP.
Isoamyl alcohol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Ecotoxicity:
Fish: Channel catfish: LC50 = 75 ppm; 96 Hr; UnspecifiedFish: Rainbow trout: LC50 = 43.8 mg/L; 96 Hr; Static bioassayFish: Fathead Minnow: LC50 = 129.0 mg/L; 96 Hr; Static bioassay (pH = 7.6-8.3)Fish: Bluegill/Sunfish: LC50 = 100.0 mg/L; 96 Hr; Static bioassayWater flea Daphnia: EC50 = 28.9 mg/L; 48 Hr; Static bioassayThe majority of the environmental releases from industrial uses are to the atmosphere; releases to water and land will be primarily lost by evaporation and will end up in the atmosphere. Release to the atmosphere may be transported long distances and will photodegrade with a half-life of a few months. Spills and other releases on land

Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

IATA
Shipping Name: Not reviewed.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not reviewed.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not reviewed.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 67-66-3: 10 lb final RQ; 4.54 kg final RQ
USA RQ: CAS# 108-95-2: 1000 lb final RQ; 454 kg final RQ

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T C
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 34 Causes burns.
R 40 Limited evidence of a carcinogenic effect.
R 48/20/21/22 Harmful : danger of serious damage to
health by prolonged exposure through inhalation, in
contact with skin and if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately
with...
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 67-66-3: 3
CAS# 108-95-2: 2
CAS# 123-51-3: 1
Canada
CAS# 67-66-3 is listed on Canadas DSL List.
CAS# 108-95-2 is listed on Canadas DSL List.
CAS# 123-51-3 is listed on Canadas DSL List.
CAS# 67-66-3 is listed on Canadas Ingredient Disclosure List.
CAS# 108-95-2 is listed on Canadas Ingredient Disclosure List.
CAS# 123-51-3 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67-66-3 is listed on the TSCA inventory.
CAS# 108-95-2 is listed on the TSCA inventory.
CAS# 123-51-3 is listed on the TSCA inventory.