Name:
Phosphate Buffer Solution
Synonym:
None Known
CAS:
1310-73-2
Section 1 - Chemical Product
MSDS Name:Phosphate Buffer Solution
Synonym:None Known
Synonym:None Known
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 1310-73-2 | Sodium hydroxide | <0.1 | 215-185-5 |
| Hazard Symbols: None Listed. Risk Phrases: None Listed. |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. Low hazard for usual industrial handling.
Inhalation:
May cause respiratory tract irritation. Low hazard for usual industrial handling.
Chronic:
No information found.
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. Low hazard for usual industrial handling.
Inhalation:
May cause respiratory tract irritation. Low hazard for usual industrial handling.
Chronic:
No information found.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1310-73-2: United Kingdom, WEL - STEL: 2 mg/m3 STEL United States OSHA: 2 mg/m3 TWA Belgium - TWA: 2 mg/m3 VLE France - VME: 2 mg/m3 VME Germany: 2 mg/m3 TWA (inhalable fraction) Japan: 2 mg/m3 Ceiling Malaysia: 2 mg/m3 Ceiling Spain: 2 mg/m3 VLA-EC CAS# 7732-18-5: CAS# 7778-77-0: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1310-73-2: United Kingdom, WEL - STEL: 2 mg/m3 STEL United States OSHA: 2 mg/m3 TWA Belgium - TWA: 2 mg/m3 VLE France - VME: 2 mg/m3 VME Germany: 2 mg/m3 TWA (inhalable fraction) Japan: 2 mg/m3 Ceiling Malaysia: 2 mg/m3 Ceiling Spain: 2 mg/m3 VLA-EC CAS# 7732-18-5: CAS# 7778-77-0: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density:
Molecular Formula: Solution
Molecular Weight: 0
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
No specific conditions to avoid noted.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
None.
Hazardous Polymerization: Will not occur.
Stable.
Conditions to Avoid:
No specific conditions to avoid noted.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
None.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1310-73-2: WB4900000 CAS# 7732-18-5: ZC0110000 CAS# 7778-77-0: TC6615500 LD50/LC50:
CAS# 1310-73-2: Draize test, rabbit, eye: 400 ug Mild; Draize test, rabbit, eye: 1% Severe; Draize test, rabbit, eye: 50 ug/24H Severe; Draize test, rabbit, eye: 1 mg/24H Severe; Draize test, rabbit, skin: 500 mg/24H Severe.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 7778-77-0: Skin, rabbit: LD50 = >4640 mg/kg.
Carcinogenicity:
Sodium hydroxide - Not listed by ACGIH, IARC, or NTP.
DI Water - Not listed by ACGIH, IARC, or NTP.
Dihydrogen potassium phosphate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 1310-73-2: WB4900000 CAS# 7732-18-5: ZC0110000 CAS# 7778-77-0: TC6615500 LD50/LC50:
CAS# 1310-73-2: Draize test, rabbit, eye: 400 ug Mild; Draize test, rabbit, eye: 1% Severe; Draize test, rabbit, eye: 50 ug/24H Severe; Draize test, rabbit, eye: 1 mg/24H Severe; Draize test, rabbit, skin: 500 mg/24H Severe.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 7778-77-0: Skin, rabbit: LD50 = >4640 mg/kg.
Carcinogenicity:
Sodium hydroxide - Not listed by ACGIH, IARC, or NTP.
DI Water - Not listed by ACGIH, IARC, or NTP.
Dihydrogen potassium phosphate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 1310-73-2: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 1310-73-2: 1
CAS# 7732-18-5: No information available.
CAS# 7778-77-0: 1
Canada
CAS# 1310-73-2 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 7778-77-0 is listed on Canadas DSL List.
CAS# 1310-73-2 is listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 7778-77-0 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1310-73-2 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 7778-77-0 is listed on the TSCA inventory.
