Name:
Potassium Hydroxide 0.1N Solution in Isopropanol
Synonym:
Titrant Standard KOH Alcoholic Solutio
CAS:
67-63-0
Section 1 - Chemical Product
MSDS Name:Potassium Hydroxide 0.1N Solution in Isopropanol
Synonym:Titrant Standard KOH Alcoholic Solutio
Synonym:Titrant Standard KOH Alcoholic Solutio
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 67-63-0 | Isopropyl alcohol | 99.74 | 200-661-7 |
| Hazard Symbols: XI F Risk Phrases: 11 36 67 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Irritating to eyes. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
May cause severe eye irritation. Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause chemical conjunctivitis and corneal damage.
Skin:
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause severe irritation and possible burns. May cause irritation with pain and stinging, especially if the skin is abraded. May cause dermatitis. May cause cyanosis of the extremities.
Ingestion:
May cause kidney damage. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Ingestion of large amounts may cause CNS depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause severe respiratory tract irritation and possible burns. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause burning sensation in the chest.
Chronic:
Prolonged or repeated inhalation may cause nosebleeds, nasal congestion, erosion of the teeth, perforation of the nasal septum, chest pain and bronchitis. Prolonged or repeated skin contact may cause defatting and dermatitis.
Highly flammable. Irritating to eyes. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
May cause severe eye irritation. Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause chemical conjunctivitis and corneal damage.
Skin:
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause severe irritation and possible burns. May cause irritation with pain and stinging, especially if the skin is abraded. May cause dermatitis. May cause cyanosis of the extremities.
Ingestion:
May cause kidney damage. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Ingestion of large amounts may cause CNS depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause severe respiratory tract irritation and possible burns. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause burning sensation in the chest.
Chronic:
Prolonged or repeated inhalation may cause nosebleeds, nasal congestion, erosion of the teeth, perforation of the nasal septum, chest pain and bronchitis. Prolonged or repeated skin contact may cause defatting and dermatitis.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Gently lift eyelids and flush continuously with water.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. This chemical poses an explosion hazard. Flammable liquid and vapor. May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. This chemical poses an explosion hazard. Flammable liquid and vapor. May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 67-63-0: United Kingdom, WEL - TWA: 400 ppm TWA; 999 mg/m3 TWA United Kingdom, WEL - STEL: 500 ppm STEL; 1250 mg/m3 STEL United States OSHA: 400 ppm TWA; 980 mg/m3 TWA Belgium - TWA: 400 ppm VLE; 997 mg/m3 VLE Belgium - STEL: 500 ppm VLE; 1248 mg/m3 VLE France - VLE: 400 ppm VLE; 980 mg/m3 VLE Germany: 200 ppm TWA; 500 mg/m3 TWA Japan: 400 ppm Ceiling; 980 mg/m3 Ceiling Malaysia: 400 ppm TWA; 983 mg/m3 TWA Netherlands: 250 ppm MAC; 650 mg/m3 MAC Russia: 10 mg/m3 TWA Spain: 400 ppm VLA-ED; 998 mg/m3 VLA-ED Spain: 500 ppm VLA-EC; 1250 mg/m3 VLA-EC CAS# 1310-58-3: United Kingdom, WEL - STEL: 2 mg/m3 STEL Belgium - STEL: 2 mg/m3 VLE France - VLE: 2 mg/m3 VLE Japan: 2 mg/m3 Ceiling Malaysia: 2 mg/m3 Ceiling Spain: 2 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A NIOSH/MSHA approved or European Standard EN 149 air purifying respirator with an organic vapor cartridge or canister may be permissible under certain circumstances where airborne concentrations are expected.
Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 67-63-0: United Kingdom, WEL - TWA: 400 ppm TWA; 999 mg/m3 TWA United Kingdom, WEL - STEL: 500 ppm STEL; 1250 mg/m3 STEL United States OSHA: 400 ppm TWA; 980 mg/m3 TWA Belgium - TWA: 400 ppm VLE; 997 mg/m3 VLE Belgium - STEL: 500 ppm VLE; 1248 mg/m3 VLE France - VLE: 400 ppm VLE; 980 mg/m3 VLE Germany: 200 ppm TWA; 500 mg/m3 TWA Japan: 400 ppm Ceiling; 980 mg/m3 Ceiling Malaysia: 400 ppm TWA; 983 mg/m3 TWA Netherlands: 250 ppm MAC; 650 mg/m3 MAC Russia: 10 mg/m3 TWA Spain: 400 ppm VLA-ED; 998 mg/m3 VLA-ED Spain: 500 ppm VLA-EC; 1250 mg/m3 VLA-EC CAS# 1310-58-3: United Kingdom, WEL - STEL: 2 mg/m3 STEL Belgium - STEL: 2 mg/m3 VLE France - VLE: 2 mg/m3 VLE Japan: 2 mg/m3 Ceiling Malaysia: 2 mg/m3 Ceiling Spain: 2 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A NIOSH/MSHA approved or European Standard EN 149 air purifying respirator with an organic vapor cartridge or canister may be permissible under certain circumstances where airborne concentrations are expected.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: none reported
pH: Not available.
Vapor Pressure: 33 mm Hg @ 20C
Viscosity: Not available.
Boiling Point: 181 deg F
Freezing/Melting Point: -128 deg F
Autoignition Temperature: Not applicable.
Flash Point: 59 deg F ( 15.00 deg C)
Explosion Limits, lower: 2.0
Explosion Limits, upper: 12.0
Decomposition Temperature: Not available.
Solubility in water: Soluble in water.
Specific Gravity/Density: 0.8
Molecular Formula: Mixture
Molecular Weight: Not available
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable. This material may be sensitive to peroxide formation.
Conditions to Avoid:
This material may be sensitive to peroxide formation., incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, oxides of potassium, acrid smoke and fumes.
Hazardous Polymerization: Has not been reported.
Stable. This material may be sensitive to peroxide formation.
Conditions to Avoid:
This material may be sensitive to peroxide formation., incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, oxides of potassium, acrid smoke and fumes.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 67-63-0: NT8050000 CAS# 1310-58-3: TT2100000 LD50/LC50:
CAS# 67-63-0: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg Mild; Inhalation, mouse: LC50 = 53000 mg/m3; Inhalation, rat: LC50 = 16000 ppm/8H; Inhalation, rat: LC50 = 72600 mg/m3; Oral, mouse: LD50 = 3600 mg/kg; Oral, mouse: LD50 = 3600 mg/kg; Oral, rabbit: LD50 = 6410 mg/kg; Oral, rat: LD50 = 5045 mg/kg; Oral, rat: LD50 = 5000 mg/kg; Skin, rabbit: LD50 = 12800 mg/kg.
CAS# 1310-58-3: Draize test, rabbit, skin: 50 mg/24H Severe; Oral, rat: LD50 = 273 mg/kg.
Carcinogenicity:
Isopropyl alcohol - Not listed by ACGIH, IARC, or NTP.
Potassium hydroxide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 67-63-0: NT8050000 CAS# 1310-58-3: TT2100000 LD50/LC50:
CAS# 67-63-0: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg Mild; Inhalation, mouse: LC50 = 53000 mg/m3; Inhalation, rat: LC50 = 16000 ppm/8H; Inhalation, rat: LC50 = 72600 mg/m3; Oral, mouse: LD50 = 3600 mg/kg; Oral, mouse: LD50 = 3600 mg/kg; Oral, rabbit: LD50 = 6410 mg/kg; Oral, rat: LD50 = 5045 mg/kg; Oral, rat: LD50 = 5000 mg/kg; Skin, rabbit: LD50 = 12800 mg/kg.
CAS# 1310-58-3: Draize test, rabbit, skin: 50 mg/24H Severe; Oral, rat: LD50 = 273 mg/kg.
Carcinogenicity:
Isopropyl alcohol - Not listed by ACGIH, IARC, or NTP.
Potassium hydroxide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Cas# 67-63-0: LC50 (96Hr.) Fathead Minnow = 94900-10400 mg/L; Flow-through condition LC50 (96 Hr.) Fathead Minnow = 61200-65500 mg/L;Flow-through condition.
Cas# 67-63-0: LC50 (96Hr.) Fathead Minnow = 94900-10400 mg/L; Flow-through condition LC50 (96 Hr.) Fathead Minnow = 61200-65500 mg/L;Flow-through condition.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
No information available.
IMO
No information available.
RID/ADR
No information available.
USA RQ: CAS# 1310-58-3: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 7 Keep container tightly closed.
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
WGK (Water Danger/Protection)
CAS# 67-63-0: 1
CAS# 1310-58-3: 1
Canada
CAS# 67-63-0 is listed on Canadas DSL List.
CAS# 1310-58-3 is listed on Canadas DSL List.
CAS# 67-63-0 is listed on Canadas Ingredient Disclosure List.
CAS# 1310-58-3 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67-63-0 is listed on the TSCA inventory.
CAS# 1310-58-3 is listed on the TSCA inventory.
