Name:
Potassium tri-sec-butylborohydride 1M solution in THF
Synonym:
CAS:
109-99-9
Section 1 - Chemical Product
MSDS Name:Potassium tri-sec-butylborohydride 1M solution in THF
Synonym:
Synonym:
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 109-99-9 | Tetrahydrofuran | 78 | 203-726-8 |
| Hazard Symbols: F C Risk Phrases: 11 15 19 34 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Contact with water liberates extremely flammable gases. May form explosive peroxides. Causes burns.Corrosive.Water-reactive.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye burns. Vapors may cause eye irritation.
Skin:
Causes skin burns. May be absorbed through the skin in harmful amounts.
Ingestion:
Causes gastrointestinal tract burns. May cause headache. May cause unconsciousness. May be harmful if swallowed. May cause central nervous system depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes chemical burns to the respiratory tract. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth.
Chronic:
Prolonged or repeated eye contact may cause conjunctivitis.
Prolonged or repeated skin contact may cause defatting and dermatitis. May cause liver and kidney damage.
Highly flammable. Contact with water liberates extremely flammable gases. May form explosive peroxides. Causes burns.Corrosive.Water-reactive.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye burns. Vapors may cause eye irritation.
Skin:
Causes skin burns. May be absorbed through the skin in harmful amounts.
Ingestion:
Causes gastrointestinal tract burns. May cause headache. May cause unconsciousness. May be harmful if swallowed. May cause central nervous system depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes chemical burns to the respiratory tract. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth.
Chronic:
Prolonged or repeated eye contact may cause conjunctivitis.
Prolonged or repeated skin contact may cause defatting and dermatitis. May cause liver and kidney damage.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
Vapors can travel to a source of ignition and flash back. Water Reactive. Material will react with water and may release a flammable and/or toxic gas. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products.
Extremely flammable liquid and vapor. Forms peroxides of unknown stability. Containers may explode in the heat of a fire.
Extinguishing Media:
Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide.
Water may be ineffective. Use dry chemical, carbon dioxide, or alcohol-resistant foam.
Vapors can travel to a source of ignition and flash back. Water Reactive. Material will react with water and may release a flammable and/or toxic gas. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products.
Extremely flammable liquid and vapor. Forms peroxides of unknown stability. Containers may explode in the heat of a fire.
Extinguishing Media:
Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide.
Water may be ineffective. Use dry chemical, carbon dioxide, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool.
Section 7 - HANDLING and STORAGE
Handling:
emsdss may develop pressure upon prolonged storage. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed.
Container should be opened by a technically qualified person. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool place in the original container and protect from sunlight. Store in a cool, dry place. Store in a tightly closed container. Keep under a nitrogen blanket. Keep away from water. Flammables-area. Refrigerator/flammables.
emsdss may develop pressure upon prolonged storage. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed.
Container should be opened by a technically qualified person. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool place in the original container and protect from sunlight. Store in a cool, dry place. Store in a tightly closed container. Keep under a nitrogen blanket. Keep away from water. Flammables-area. Refrigerator/flammables.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 54575-49-4: Personal Protective Equipment Eyes: Wear safety glasses and chemical goggles if splashing is possible.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 54575-49-4: Personal Protective Equipment Eyes: Wear safety glasses and chemical goggles if splashing is possible.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear slightly yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: -17 deg C ( 1.40 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: reacts with water
Specific Gravity/Density: .9130g/cm3
Molecular Formula: C12H28BK
Molecular Weight: 222.26
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Prolonged exposure to air and sunlight may form unstable peroxides.
Explosive peroxides may form on concentration. Peroxides can be detonated by friction, impact, or heating. Peroxide formation may occur in containers that have been opened and remain in storage.
Normally stable; however, on long term storage, materials containing similar functional groups form peroxides of unknown stability.
Conditions to Avoid:
Normally stable; however, on long term storage, materials containing similar functional groups form peroxides of unknown stability., incompatible materials, light, ignition sources, exposure to air, contact with water, exposure to moist air or water.
Incompatibilities with Other Materials:
It is explosive with potassium hydroxide, sodium hydroxide, and sodium tetrahydroaluminate since caustic alkalies deplete the inhibitor. Reacts with potassium dioxide 2-aminophenol to form an explosive product. Reacts violently with metal halides. Forms explosive hydrogen gas with borane or lithium tetrahydroaluminate and reacts vigorously with bromine and calcium hydride+heat. Incompatible with sulfinyl chloride and oxidizing materials. Hazardous polymerization may occur in the presence of cationic initiators such as strong proton acids or selected Lewis acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, oxides of boron, borane.
Hazardous Polymerization: Has not been reported.
Prolonged exposure to air and sunlight may form unstable peroxides.
Explosive peroxides may form on concentration. Peroxides can be detonated by friction, impact, or heating. Peroxide formation may occur in containers that have been opened and remain in storage.
Normally stable; however, on long term storage, materials containing similar functional groups form peroxides of unknown stability.
Conditions to Avoid:
Normally stable; however, on long term storage, materials containing similar functional groups form peroxides of unknown stability., incompatible materials, light, ignition sources, exposure to air, contact with water, exposure to moist air or water.
Incompatibilities with Other Materials:
It is explosive with potassium hydroxide, sodium hydroxide, and sodium tetrahydroaluminate since caustic alkalies deplete the inhibitor. Reacts with potassium dioxide 2-aminophenol to form an explosive product. Reacts violently with metal halides. Forms explosive hydrogen gas with borane or lithium tetrahydroaluminate and reacts vigorously with bromine and calcium hydride+heat. Incompatible with sulfinyl chloride and oxidizing materials. Hazardous polymerization may occur in the presence of cationic initiators such as strong proton acids or selected Lewis acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, oxides of boron, borane.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 109-99-9: LU5950000 CAS# 54575-49-4 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 54575-49-4.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Potassium tri-sec-butylborohydride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 109-99-9: LU5950000 CAS# 54575-49-4 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 54575-49-4.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Potassium tri-sec-butylborohydride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Blue-green algae, growth inhibition microcystis=225 mg/L (PH=7); Protozoa, cell multiplication inhibition test=858 mg/L.
Cas# 109-00-0: LC50(96Hr.) Fathead Minnow = 2160 mg/L
Blue-green algae, growth inhibition microcystis=225 mg/L (PH=7); Protozoa, cell multiplication inhibition test=858 mg/L.
Cas# 109-00-0: LC50(96Hr.) Fathead Minnow = 2160 mg/L
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: METAL ALKYLS, N.O.S.*
Hazard Class: 4.2
UN Number: 2003
Packing Group:
IMO
Shipping Name: METAL ALKYLS, N.O.S.
Hazard Class: 4.2
UN Number: 2003
Packing Group: I
RID/ADR
Shipping Name: METAL ALKYLS, N.O.S.
Hazard Class: 4.2
UN Number: 2003
Packing group: I
USA RQ: CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 15 Contact with water liberates extremely
flammable gases.
R 19 May form explosive peroxides.
R 34 Causes burns.
Safety Phrases:
S 7/8 Keep container tightly closed and dry.
S 16 Keep away from sources of ignition - No
smoking.
S 25 Avoid contact with eyes.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 109-99-9: 1
CAS# 54575-49-4: No information available.
Canada
CAS# 109-99-9 is listed on Canadas DSL List.
CAS# 54575-49-4 is listed on Canadas NDSL List.
CAS# 109-99-9 is listed on Canadas Ingredient Disclosure List.
CAS# 54575-49-4 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 109-99-9 is listed on the TSCA inventory.
CAS# 54575-49-4 is listed on the TSCA inventory.
