Name:
Prenol from sea buckthorn (hippophae) 80 mg/ml solution in CCl4
Synonym:
None
CAS:
0-01-1
Section 1 - Chemical Product
MSDS Name:Prenol from sea buckthorn (hippophae) 80 mg/ml solution in CCl4
Synonym:None
Synonym:None
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 0-01-1 | Carbon tetrachloride | 92.0 | 200-262-8 |
| Hazard Symbols: T N Risk Phrases: 23/24/25 40 59 48/23 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Dangerous for the ozone layer.
Toxic : danger of serious damage to health by prolonged exposure through inhalation.Cancer suspect agent.
Potential Health Effects
Eye:
May cause eye irritation. May cause temporary visual impairment.
Skin:
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause tremors and convulsions. May cause effects similar to those of acute inhalation. Substance is a hepatotoxin and is capable of producing a toxic effect on the liver.
Inhalation:
May cause liver and kidney damage. May cause adverse central nervous system effects including headache, convulsions, and possible death.
May cause heart disturbances, possibly leading to cardiac arrest and death. May cause liver abnormalities. May cause cardiac abnormalities.
Chronic:
Chronic exposure to organic solvents has been associated with various neurotoxic effects including permanent brain and nervous system damage. Chronic ingestion may cause effects similar to those of acute ingestion. May cause cancer according to animal studies.
Chronic exposure may cause visual disturbances.
Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Dangerous for the ozone layer.
Toxic : danger of serious damage to health by prolonged exposure through inhalation.Cancer suspect agent.
Potential Health Effects
Eye:
May cause eye irritation. May cause temporary visual impairment.
Skin:
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause tremors and convulsions. May cause effects similar to those of acute inhalation. Substance is a hepatotoxin and is capable of producing a toxic effect on the liver.
Inhalation:
May cause liver and kidney damage. May cause adverse central nervous system effects including headache, convulsions, and possible death.
May cause heart disturbances, possibly leading to cardiac arrest and death. May cause liver abnormalities. May cause cardiac abnormalities.
Chronic:
Chronic exposure to organic solvents has been associated with various neurotoxic effects including permanent brain and nervous system damage. Chronic ingestion may cause effects similar to those of acute ingestion. May cause cancer according to animal studies.
Chronic exposure may cause visual disturbances.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Extinguishing Media:
Do NOT get water inside containers. Do NOT use straight streams of water. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use water spray, fog or regular foam. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Extinguishing Media:
Do NOT get water inside containers. Do NOT use straight streams of water. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use water spray, fog or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition.
Provide ventilation. Do not get water inside containers.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition.
Provide ventilation. Do not get water inside containers.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood.
Storage:
Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not store near alkaline substances.
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood.
Storage:
Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not store near alkaline substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 0-01-1: CAS# 56-23-5: United Kingdom, WEL - TWA: 2 ppm TWA; 13 mg/m3 TWA United Kingdom, WEL - STEL: 6 ppm STEL; 39 mg/m3 STEL United States OSHA: 10 ppm TWA; 25 ppm Ceiling Belgium - TWA: 5 ppm VLE; 31 mg/m3 VLE Belgium - STEL: 10 ppm VLE; 64 mg/m3 VLE France - VME: 2 ppm VME; 12 mg/m3 VME France - VLE: 10 ppm VLE; 60 mg/m3 VLE Germany: 2.5 ppm TWA (large technical manufacture and use); 16 mg TWA (large technical Germany: Skin absorber Japan: 5 ppm OEL; 31 mg/m3 OEL Malaysia: 5 ppm TWA; 31 mg/m3 TWA Netherlands: 2 ppm MAC; 12.6 mg/m3 MAC Russia: 20 mg/m3 TWA Spain: 5 ppm VLA-ED; 32 mg/m3 VLA-ED Spain: 10 ppm VLA-EC; 64 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear polyvinyl chloride gloves, apron, and/or clothing. Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear polyvinyl chloride gloves, apron, and/or clothing. Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 0-01-1: CAS# 56-23-5: United Kingdom, WEL - TWA: 2 ppm TWA; 13 mg/m3 TWA United Kingdom, WEL - STEL: 6 ppm STEL; 39 mg/m3 STEL United States OSHA: 10 ppm TWA; 25 ppm Ceiling Belgium - TWA: 5 ppm VLE; 31 mg/m3 VLE Belgium - STEL: 10 ppm VLE; 64 mg/m3 VLE France - VME: 2 ppm VME; 12 mg/m3 VME France - VLE: 10 ppm VLE; 60 mg/m3 VLE Germany: 2.5 ppm TWA (large technical manufacture and use); 16 mg TWA (large technical Germany: Skin absorber Japan: 5 ppm OEL; 31 mg/m3 OEL Malaysia: 5 ppm TWA; 31 mg/m3 TWA Netherlands: 2 ppm MAC; 12.6 mg/m3 MAC Russia: 20 mg/m3 TWA Spain: 5 ppm VLA-ED; 32 mg/m3 VLA-ED Spain: 10 ppm VLA-EC; 64 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear polyvinyl chloride gloves, apron, and/or clothing. Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear polyvinyl chloride gloves, apron, and/or clothing. Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: ethereal odor
pH: Not available.
Vapor Pressure: 121 mbar @ 20 C
Viscosity: 0.97 PAS 20 deg C
Boiling Point: 76 deg C @ 760.00mm Hg
Freezing/Melting Point: -23 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >100 deg C
Solubility in water: soluble in ethanol, ether and acetone
Specific Gravity/Density: 1.5940g/cm3
Molecular Formula: CCl4
Molecular Weight: 153.82
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Mechanical shock, incompatible materials, light, excess heat.
Incompatibilities with Other Materials:
Aluminum, bromine trifluoride, calcium hypochlorite, dimethyl formamide, ethylene oxide, fluorine, lithium, magnesium, potassium, potassium-tert-butoxide, silver perchlorate, sodium, uranium, chlorine trifluoride, dinitrogen tetraoxide, methanol.
Hazardous Decomposition Products:
Hydrogen chloride, chlorine, phosgene, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Mechanical shock, incompatible materials, light, excess heat.
Incompatibilities with Other Materials:
Aluminum, bromine trifluoride, calcium hypochlorite, dimethyl formamide, ethylene oxide, fluorine, lithium, magnesium, potassium, potassium-tert-butoxide, silver perchlorate, sodium, uranium, chlorine trifluoride, dinitrogen tetraoxide, methanol.
Hazardous Decomposition Products:
Hydrogen chloride, chlorine, phosgene, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 0-01-1 unlisted.
CAS# 56-23-5: FG4900000 LD50/LC50:
Not available.
CAS# 56-23-5: Dermal, guinea pig: LD50 = >9400 uL/kg; Draize test, rabbit, eye: 2200 ug/30S Mild; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 4 mg Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 9526 ppm/8H; Inhalation, mouse: LC50 = 34500 mg/m3/2H; Inhalation, rat: LC50 = 8000 ppm/4H; Inhalation, rat: LC50 = 46000 mg/m3/6H; Oral, mouse: LD50 = 7749 mg/kg; Oral, rabbit: LD50 = 5760 mg/kg; Oral, rat: LD50 = 2350 mg/kg; Skin, rabbit: LD50 = >20 gm/kg; Skin, rat: LD50 = 5070 mg/kg.
Carcinogenicity:
Prenol, from sea buckthorn (hippophae) - Not listed by ACGIH, IARC, or NTP.
Carbon tetrachloride - ACGIH: A2 - Suspected Human Carcinogen California: carcinogen, initial date 10/1/87 NTP: Suspect carcinogen IARC: Group 2B carcinogen Other:
See actual entry in RTECS for complete information.
CAS# 0-01-1 unlisted.
CAS# 56-23-5: FG4900000 LD50/LC50:
Not available.
CAS# 56-23-5: Dermal, guinea pig: LD50 = >9400 uL/kg; Draize test, rabbit, eye: 2200 ug/30S Mild; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 4 mg Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 9526 ppm/8H; Inhalation, mouse: LC50 = 34500 mg/m3/2H; Inhalation, rat: LC50 = 8000 ppm/4H; Inhalation, rat: LC50 = 46000 mg/m3/6H; Oral, mouse: LD50 = 7749 mg/kg; Oral, rabbit: LD50 = 5760 mg/kg; Oral, rat: LD50 = 2350 mg/kg; Skin, rabbit: LD50 = >20 gm/kg; Skin, rat: LD50 = 5070 mg/kg.
Carcinogenicity:
Prenol, from sea buckthorn (hippophae) - Not listed by ACGIH, IARC, or NTP.
Carbon tetrachloride - ACGIH: A2 - Suspected Human Carcinogen California: carcinogen, initial date 10/1/87 NTP: Suspect carcinogen IARC: Group 2B carcinogen Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 20.8-41.4 mg/L; 96 Hr.; Flow-through; 21.7 degrees CFish: Bluegill/Sunfish: LC50 = 27-125 mg/L; 96 Hr.; Static Conditions; 23 degrees CBacteria: Phytobacterium phosphoreum: EC50 = 6.0 mg/L; Not available; Microtox testBacteria: Phytobacterium phosphoreum: EC50 = 33.0 mg/L; 30 minutes; Microtox test
Fish: Fathead Minnow: LC50 = 20.8-41.4 mg/L; 96 Hr.; Flow-through; 21.7 degrees CFish: Bluegill/Sunfish: LC50 = 27-125 mg/L; 96 Hr.; Static Conditions; 23 degrees CBacteria: Phytobacterium phosphoreum: EC50 = 6.0 mg/L; Not available; Microtox testBacteria: Phytobacterium phosphoreum: EC50 = 33.0 mg/L; 30 minutes; Microtox test
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 56-23-5: 10 lb final RQ; 4.54 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 40 Limited evidence of a carcinogenic effect.
R 48/23 Toxic : danger of serious damage to health
by prolonged exposure through inhalation.
R 59 Dangerous for the ozone layer.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 23 Do not inhale gas/fumes/vapour/spray.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 59 Refer to manufacturer/supplier for information
on recovery/recycling.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 0-01-1: No information available.
CAS# 56-23-5: 3
Canada
CAS# 56-23-5 is listed on Canadas DSL List.
CAS# 0-01-1 is not listed on Canadas Ingredient Disclosure List.
CAS# 56-23-5 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 0-01-1 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 56-23-5 is listed on the TSCA inventory.
