MSDS Name:Pyrene 98+%(gc)
Synonym:Benzo[def]phenanthren

EMERGENCY OVERVIEW
May cause cancer.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
Causes skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis. Dermal applications may cause hyperemia (an excess of blood in a part), weight loss, and hematopoietic changes.
Ingestion:
May cause digestive tract disturbances. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
Inhalation:
May be fatal if inhaled. Causes respiratory tract irritation.
Inhalation of dust may cause respiratory tract irritation.
Chronic:
May cause cancer according to animal studies. Chronic effects may include leukocytosis and lengthened chronaxy of the leg muscle flexors.

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Do not let this chemical enter the environment.

Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 129-00-0: United States OSHA: 0.2 mg/m3 TWA (as benzene soluble fraction) (listed under Coal tar pitches).
Belgium - TWA: (listed as coal tar pitches): 0.2 mg/m3 VLE France - VME: (listed as coal tar pitches): 0.2 mg/m3 VME (vapors mists, benzene-soluble fraction) Germany: (listed as coal tar pitches): 0.2 mg/m3 VME (vapors and mists, benzene-soluble fraction) Malaysia: (listed as coal tar pitches): 0.2 mg/m3 TWA (as benzene solubles) Russia: 0.03 mg/m3 TWA Spain: (listed as coal tar pitches): 0.2 mg/m3 VLA-ED (benzene soluble fraction) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Physical State: Powder
Color: yellow
Odor: None reported.
pH: Not available.
Vapor Pressure: < 1 mm Hg @20C
Viscosity: Not available.
Boiling Point: 404 deg C @ 760.00mmHg
Freezing/Melting Point: 156 deg C
Autoignition Temperature: Not available.
Flash Point: 210 deg C ( 410.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 1.271
Specific Gravity/Density:
Molecular Formula: C16H10
Molecular Weight: 202.25

Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acrid smoke and fumes.
Hazardous Polymerization: Has not been reported.

RTECS#:
CAS# 129-00-0: UR2450000 UR2450100 LD50/LC50:
CAS# 129-00-0: Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = 170 mg/m3; Inhalation, rat: LC50 = 170 mg/m3; Oral, mouse: LD50 = 800 mg/kg; Oral, rat: LD50 = 2700 mg/kg.
Carcinogenicity:
Pyrene, ca - NTP: Known carcinogen (listed as Coal tar pitches).
IARC: Group 1 carcinogen (listed as Coal tar pitches).
Other:
See actual entry in RTECS for complete information.

Ecotoxicity:
Water flea Daphnia: EC50 = 1.8 mg/L; 48 Hr.; Unspecified

Dispose of in a manner consistent with federal, state, and local regulations.

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 129-00-0: 5000 lb final RQ; 2270 kg final RQ

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 45 May cause cancer.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 129-00-0: No information available.
Canada
CAS# 129-00-0 is listed on Canadas DSL List.
CAS# 129-00-0 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 129-00-0 is listed on the TSCA inventory.