Name:
Quinidine anhydrous ca.95% remainder dihydroquinidine
Synonym:
Cinchonan-9-ol, 6-methoxy, (9S)-; Conchinin; Conquinine; (9S)-6-Methoxycinchonan-9-ol; 6-Methoxy-alpha-95-vinyl-2-quinuclidinyl)-4-quinolinemethanol; Pitayine; (+)-Qinidine; (8R,9S)-Qinidine; beta-Quinin
CAS:
56-54-2
Section 1 - Chemical Product
MSDS Name:Quinidine anhydrous ca.95% remainder dihydroquinidine
Synonym:Cinchonan-9-ol, 6-methoxy, (9S)-; Conchinin; Conquinine; (9S)-6-Methoxycinchonan-9-ol; 6-Methoxy-alpha-95-vinyl-2-quinuclidinyl)-4-quinolinemethanol; Pitayine; (+)-Qinidine; (8R,9S)-Qinidine; beta-Quinin
Synonym:Cinchonan-9-ol, 6-methoxy, (9S)-; Conchinin; Conquinine; (9S)-6-Methoxycinchonan-9-ol; 6-Methoxy-alpha-95-vinyl-2-quinuclidinyl)-4-quinolinemethanol; Pitayine; (+)-Qinidine; (8R,9S)-Qinidine; beta-Quinin
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 56-54-2 | Quinidine anhydrous, remainder dihydro | ca. 100 | 200-279-0 |
| Hazard Symbols: XN Risk Phrases: 22 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful if swallowed.Light sensitive.Toxic.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
Causes mild skin irritation.
Ingestion:
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cardiac effects such as heart blocks, arrhythmias, shock and possible death due to cardiovascular collapse.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Chronic exposure may cause blood effects.
Harmful if swallowed.Light sensitive.Toxic.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
Causes mild skin irritation.
Ingestion:
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cardiac effects such as heart blocks, arrhythmias, shock and possible death due to cardiovascular collapse.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Chronic exposure may cause blood effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting only when instructed to do so by a physician.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician:
Treatment options include ipecac/lavage, activated charcoal, cathartics--admisitered within two hours of ingestion.
Skin:
Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting only when instructed to do so by a physician.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician:
Treatment options include ipecac/lavage, activated charcoal, cathartics--admisitered within two hours of ingestion.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use carbon dioxide, dry chemical powder or water spray.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use carbon dioxide, dry chemical powder or water spray.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Wash area with soap and water. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Provide ventilation.
Spills/Leaks:
Wash area with soap and water. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale. Use only in a chemical fume hood. Do not breathe dust.
Storage:
Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale. Use only in a chemical fume hood. Do not breathe dust.
Storage:
Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 56-54-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 56-54-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Powder
Color: white to off-white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 174.00 - 175.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: 1g/2000ml cold water
Specific Gravity/Density: Not available.
Molecular Formula: C20H24N2O2
Molecular Weight: 324.41
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Darkens on exposure to light.
Conditions to Avoid:
Incompatible materials, light, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents, direct light.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures. Darkens on exposure to light.
Conditions to Avoid:
Incompatible materials, light, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents, direct light.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 56-54-2: VA4725000 LD50/LC50:
CAS# 56-54-2: Draize test, rabbit, skin: 3% Mild; Oral, mouse: LD50 = 535 mg/kg; Oral, rat: LD50 = 263 mg/kg.
Carcinogenicity:
Quinidine anhydrous, remainder dihydroquinidine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 56-54-2: VA4725000 LD50/LC50:
CAS# 56-54-2: Draize test, rabbit, skin: 3% Mild; Oral, mouse: LD50 = 535 mg/kg; Oral, rat: LD50 = 263 mg/kg.
Carcinogenicity:
Quinidine anhydrous, remainder dihydroquinidine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
S 22 Do not breathe dust.
S 36 Wear suitable protective clothing.
WGK (Water Danger/Protection)
CAS# 56-54-2: 2
Canada
CAS# 56-54-2 is listed on Canadas NDSL List.
CAS# 56-54-2 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 56-54-2 is listed on the TSCA inventory.
