Name:
Saline/TRIS/EDTA/Triton X-100 (pH 8.0) 1 x Solution
Synonym:
None
CAS:
0-01-1
Section 1 - Chemical Product
MSDS Name:Saline/TRIS/EDTA/Triton X-100 (pH 8.0) 1 x Solution
Synonym:None
Synonym:None
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 0-01-1 | Ethylenediaminetetraacetic acid (EDTA) | <1.0 | 200-449-4 |
| Hazard Symbols: None Listed. Risk Phrases: None Listed. |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May cause an allergic reaction in certain individuals.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
May cause respiratory tract irritation.
Chronic:
No information found.
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May cause an allergic reaction in certain individuals.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
May cause respiratory tract irritation.
Chronic:
No information found.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 0-01-1: CAS# 60-00-4: CAS# 7647-01-0: United Kingdom, WEL - TWA: 1 ppm TWA (aerosol mist and gas); 2 mg TWA (aerosol mist and gas) United Kingdom, WEL - STEL: 5 ppm STEL (aerosol mist and gas); 8 mg/m3 STEL (aerosol mist and gas) United States OSHA: ; 5 ppm Ceiling; 7 mg/m3 Ceiling Belgium - TWA: 5 ppm VLE; 8 mg/m3 VLE Belgium - STEL: 10 ppm VLE; 15 mg/m3 VLE France - VLE: 5 ppm VLE; 7.5 mg/m3 VLE Germany: 8 mg/m3 TWA Japan: 5 ppm Ceiling; 7.5 mg/m3 Ceiling Malaysia: 5 ppm Ceiling; 7.5 mg/m3 Ceiling Netherlands: 10 ppm STEL; 15 mg/m3 STEL Netherlands: 5 ppm MAC; 8 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 5 ppm VLA-ED; 7.6 mg/m3 VLA-ED Spain: 10 ppm VLA-EC; 15 mg/m3 VLA-EC CAS# 7647-14-5: Russia: 5 mg/m3 TWA CAS# 7732-18-5: CAS# 9002-93-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 0-01-1: CAS# 60-00-4: CAS# 7647-01-0: United Kingdom, WEL - TWA: 1 ppm TWA (aerosol mist and gas); 2 mg TWA (aerosol mist and gas) United Kingdom, WEL - STEL: 5 ppm STEL (aerosol mist and gas); 8 mg/m3 STEL (aerosol mist and gas) United States OSHA: ; 5 ppm Ceiling; 7 mg/m3 Ceiling Belgium - TWA: 5 ppm VLE; 8 mg/m3 VLE Belgium - STEL: 10 ppm VLE; 15 mg/m3 VLE France - VLE: 5 ppm VLE; 7.5 mg/m3 VLE Germany: 8 mg/m3 TWA Japan: 5 ppm Ceiling; 7.5 mg/m3 Ceiling Malaysia: 5 ppm Ceiling; 7.5 mg/m3 Ceiling Netherlands: 10 ppm STEL; 15 mg/m3 STEL Netherlands: 5 ppm MAC; 8 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 5 ppm VLA-ED; 7.6 mg/m3 VLA-ED Spain: 10 ppm VLA-EC; 15 mg/m3 VLA-EC CAS# 7647-14-5: Russia: 5 mg/m3 TWA CAS# 7732-18-5: CAS# 9002-93-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: Solution
Molecular Weight: 0
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, irritating and toxic fumes and gases, sodium oxide.
Hazardous Polymerization: Has not been reported.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, irritating and toxic fumes and gases, sodium oxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 0-01-1 unlisted.
CAS# 60-00-4: AH4025000 CAS# 7647-01-0: MW4025000 MW4031000 CAS# 7647-14-5: VZ4725000 CAS# 7732-18-5: ZC0110000 CAS# 9002-93-1: MD0907700 YM0616666 YM0683332 LD50/LC50:
Not available.
CAS# 60-00-4: Oral, mouse: LD50 = 30 mg/kg.
CAS# 7647-01-0: Inhalation, mouse: LC50 = 1108 ppm/1H; Inhalation, mouse: LC50 = 20487 mg/m3/5M; Inhalation, mouse: LC50 = 3940 mg/m3/30M; Inhalation, mouse: LC50 = 8300 mg/m3/30M; Inhalation, rat: LC50 = 3124 ppm/1H; Inhalation, rat: LC50 = 60938 mg/m3/5M; Inhalation, rat: LC50 = 7004 mg/m3/30M; Inhalation, rat: LC50 = 45000 mg/m3/5M; Inhalation, rat: LC50 = 8300 mg/m3/30M; Oral, rabbit: LD50 = 900 mg/kg.
CAS# 7647-14-5: Draize test, rabbit, eye: 100 mg Mild; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, skin: 50 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >42 gm/m3/1H; Oral, mouse: LD50 = 4 gm/kg; Oral, rat: LD50 = 3000 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 9002-93-1: Draize test, rabbit, eye: 10 uL/24H Moderate; Draize test, rabbit, skin: 500 uL/24H Mild; Oral, rat: LD50 = 1800 mg/kg; Oral, rat: LD50 = 3800 mg/kg; Oral, rat: LD50 = 1900 mg/kg.
Carcinogenicity:
Tris Base - Not listed by ACGIH, IARC, or NTP.
Ethylenediaminetetraacetic acid (EDTA) - Not listed by ACGIH, IARC, or NTP.
Hydrogen chloride - Not listed by ACGIH, IARC, or NTP.
Sodium chloride - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Ethoxylated p-tert-octylphenol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 0-01-1 unlisted.
CAS# 60-00-4: AH4025000 CAS# 7647-01-0: MW4025000 MW4031000 CAS# 7647-14-5: VZ4725000 CAS# 7732-18-5: ZC0110000 CAS# 9002-93-1: MD0907700 YM0616666 YM0683332 LD50/LC50:
Not available.
CAS# 60-00-4: Oral, mouse: LD50 = 30 mg/kg.
CAS# 7647-01-0: Inhalation, mouse: LC50 = 1108 ppm/1H; Inhalation, mouse: LC50 = 20487 mg/m3/5M; Inhalation, mouse: LC50 = 3940 mg/m3/30M; Inhalation, mouse: LC50 = 8300 mg/m3/30M; Inhalation, rat: LC50 = 3124 ppm/1H; Inhalation, rat: LC50 = 60938 mg/m3/5M; Inhalation, rat: LC50 = 7004 mg/m3/30M; Inhalation, rat: LC50 = 45000 mg/m3/5M; Inhalation, rat: LC50 = 8300 mg/m3/30M; Oral, rabbit: LD50 = 900 mg/kg.
CAS# 7647-14-5: Draize test, rabbit, eye: 100 mg Mild; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, eye: 10 mg Moderate; Draize test, rabbit, skin: 50 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >42 gm/m3/1H; Oral, mouse: LD50 = 4 gm/kg; Oral, rat: LD50 = 3000 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 9002-93-1: Draize test, rabbit, eye: 10 uL/24H Moderate; Draize test, rabbit, skin: 500 uL/24H Mild; Oral, rat: LD50 = 1800 mg/kg; Oral, rat: LD50 = 3800 mg/kg; Oral, rat: LD50 = 1900 mg/kg.
Carcinogenicity:
Tris Base - Not listed by ACGIH, IARC, or NTP.
Ethylenediaminetetraacetic acid (EDTA) - Not listed by ACGIH, IARC, or NTP.
Hydrogen chloride - Not listed by ACGIH, IARC, or NTP.
Sodium chloride - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Ethoxylated p-tert-octylphenol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
No information available.
IMO
No information available.
RID/ADR
No information available.
USA RQ: CAS# 60-00-4: 5000 lb final RQ; 2270 kg final RQ
USA RQ: CAS# 7647-01-0: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 0-01-1: No information available.
CAS# 60-00-4: 2
CAS# 7647-01-0: 1
CAS# 7647-14-5: 0
CAS# 7732-18-5: No information available.
CAS# 9002-93-1: 1
Canada
CAS# 60-00-4 is listed on Canadas DSL List.
CAS# 7647-01-0 is listed on Canadas DSL List.
CAS# 7647-14-5 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 9002-93-1 is listed on Canadas DSL List.
CAS# 0-01-1 is not listed on Canadas Ingredient Disclosure List.
CAS# 60-00-4 is not listed on Canadas Ingredient Disclosure List.
CAS# 7647-01-0 is listed on Canadas Ingredient Disclosure List.
CAS# 7647-14-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 9002-93-1 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 0-01-1 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 60-00-4 is listed on the TSCA inventory.
CAS# 7647-01-0 is listed on the TSCA inventory.
CAS# 7647-14-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 9002-93-1 is listed on the TSCA inventory.
