MSDS Name:Sodium acetate buffer solution
Synonym:Mixture

EMERGENCY OVERVIEW
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. Contact with liquid or vapor causes severe burns and possible irreversible eye damage.
Skin:
Causes skin burns.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.
Inhalation:
Irritation may lead to chemical pneumonitis and pulmonary edema.
Causes chemical burns to the respiratory tract.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Repeated inhalation may cause chronic bronchitis. Repeated exposure may cause erosion of teeth. May cause reproductive and fetal effects.

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:

General Information:
Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Reacts with most metals to form highly flammable hydrogen gas which can form explosive mixtures with air.
Extinguishing Media:
Use water fog, dry chemical, carbon dioxide, or regular foam.

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.

Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get on skin or in eyes. Do not ingest or inhale.
Storage:
Keep away from heat, sparks, and flame. Store in a cool, dry, well-ventilated area away from incompatible substances. Store in a suitable container in a dry area above the substances freezing point.

Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 64-19-7: United States OSHA: 10 ppm TWA; 25 mg/m3 TWA Belgium - TWA: 10 ppm VLE; 25 mg/m3 VLE Belgium - STEL: 15 ppm VLE; 38 mg/m3 VLE France - VLE: 10 ppm VLE; 25 mg/m3 VLE Germany: 10 ppm TWA; 25 mg/m3 TWA Japan: 10 ppm OEL; 25 mg/m3 OEL Malaysia: 10 ppm TWA; 25 mg/m3 TWA Netherlands: 10 ppm MAC; 25 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 10 ppm VLA-ED; 25 mg/m3 VLA-ED Spain: 15 ppm VLA-EC; 37 mg/m3 VLA-EC CAS# 127-09-3: CAS# 6131-90-4: CAS# 7732-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Physical State: Liquid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:

Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Acetic acid is incompatible with acetaldehyde, 2-aminoethanol, ammonium nitrate, bromine pentafluoride, chlorine trifluoride, chlorosulfonic acid, chromic acid, chromic anhydride + acetic anhydride, diallyl methyl carbinol + ozone, ethylene diamine, ethyleneimine, hydrogen peroxide, nitric acid, nitric acid + acetone, oleum, perchloric acid, permanganates, phosphorus isocyanate, phosphorus trichloride, potassium hydroxide, potassium-t-butoxide, sodium hydroxide, sodium peroxide, and xylene. See NFPA Fire Protection Guide for specifics. Sodium acetate is incompatible with strong oxidizing agents. Explosive mixtures may be formed with fluorine or potassium nitrite.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

RTECS#:
CAS# 64-19-7: AF1225000 CAS# 127-09-3: AJ4300010 CAS# 6131-90-4: AJ4580000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 64-19-7: Draize test, rabbit, skin: 50 mg/24H Mild; Inhalation, mouse: LC50 = 5620 ppm/1H; Oral, rat: LD50 = 3310 mg/kg; Skin, rabbit: LD50 = 1060 uL/kg.
CAS# 127-09-3: Draize test, rabbit, eye: 10 mg Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >30 gm/m3/1H; Oral, mouse: LD50 = 6891 mg/kg; Oral, rat: LD50 = 3530 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
CAS# 6131-90-4.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Acetic acid - Not listed by ACGIH, IARC, or NTP.
Sodium acetate - Not listed by ACGIH, IARC, or NTP.
Acetate, sodium, trihydrate - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Ecotoxicity:
Bluegill (fresh water) TLm=75 ppm/96H Goldfish (fresh water) TLm=100 ppm/96H Shrimp (aerated water) LC50=100-330 ppm/48H

Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

IATA
Shipping Name: ACETIC ACID SOLUTION
Hazard Class: 8
UN Number: 2790
Packing Group: II
IMO
Shipping Name: ACETIC ACID SOLUTION
Hazard Class: 8
UN Number: 2790
Packing Group: II
RID/ADR
Shipping Name: ACETIC ACID SOLUTION
Hazard Class: 8
UN Number: 2790
Packing group: II
USA RQ: CAS# 64-19-7: 5000 lb final RQ; 2270 kg final RQ

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 64-19-7: 1
CAS# 127-09-3: 1
CAS# 6131-90-4: 1
CAS# 7732-18-5: No information available.
Canada
CAS# 64-19-7 is listed on Canadas DSL List.
CAS# 127-09-3 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 64-19-7 is listed on Canadas Ingredient Disclosure List.
CAS# 127-09-3 is not listed on Canadas Ingredient Disclosure List.
CAS# 6131-90-4 is not listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 64-19-7 is listed on the TSCA inventory.
CAS# 127-09-3 is listed on the TSCA inventory.
CAS# 6131-90-4 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).
CAS# 7732-18-5 is listed on the TSCA inventory.