Name:
Sodium Acetate Buffer Solution with 5.0% Triton X-100
Synonym:
Mixtur
CAS:
64-19-7
Section 1 - Chemical Product
MSDS Name:Sodium Acetate Buffer Solution with 5.0% Triton X-100
Synonym:Mixtur
Synonym:Mixtur
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 64-19-7 | Acetic acid | 48 | 200-580-7 |
| Hazard Symbols: C Risk Phrases: 35 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes severe burns.Corrosive.
Potential Health Effects
Eye:
Contact with liquid or vapor causes severe burns and possible irreversible eye damage.
Skin:
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Causes severe skin irritation and burns. May be harmful if absorbed through the skin.
Contact with the skin may cause blackening and hyperkeratosis of the skin of the hands.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. Causes severe pain, nausea, vomiting, diarrhea, and shock.
Inhalation:
Effects may be delayed. Irritation may lead to chemical pneumonitis and pulmonary edema. Causes chemical burns to the respiratory tract.
Exposure may lead to bronchitis, pharyngitis, and dental erosion. May be absorbed through the lungs.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Repeated inhalation may cause chronic bronchitis. Repeated exposure may cause erosion of teeth. May cause reproductive and fetal effects.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure may cause corneal erosion, conjunctivitis, and possible blindness.
Causes severe burns.Corrosive.
Potential Health Effects
Eye:
Contact with liquid or vapor causes severe burns and possible irreversible eye damage.
Skin:
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Causes severe skin irritation and burns. May be harmful if absorbed through the skin.
Contact with the skin may cause blackening and hyperkeratosis of the skin of the hands.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. Causes severe pain, nausea, vomiting, diarrhea, and shock.
Inhalation:
Effects may be delayed. Irritation may lead to chemical pneumonitis and pulmonary edema. Causes chemical burns to the respiratory tract.
Exposure may lead to bronchitis, pharyngitis, and dental erosion. May be absorbed through the lungs.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Repeated inhalation may cause chronic bronchitis. Repeated exposure may cause erosion of teeth. May cause reproductive and fetal effects.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure may cause corneal erosion, conjunctivitis, and possible blindness.
Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with pre-existing skin disorders or impaired respiratory or pulmonary function may be at increased risk to the effects of this substance. Treat symptomatically and supportively.
Antidote: No specific antidote exists.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with pre-existing skin disorders or impaired respiratory or pulmonary function may be at increased risk to the effects of this substance. Treat symptomatically and supportively.
Antidote: No specific antidote exists.
Section 5 - FIRE FIGHTING MEASURES
General Information:
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Reacts with most metals to form highly flammable hydrogen gas which can form explosive mixtures with air.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May polymerize explosively when involved in a fire. Containers may explode when heated.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water fog, dry chemical, carbon dioxide, or regular foam. Do NOT get water inside containers. Do NOT use straight streams of water.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Reacts with most metals to form highly flammable hydrogen gas which can form explosive mixtures with air.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May polymerize explosively when involved in a fire. Containers may explode when heated.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water fog, dry chemical, carbon dioxide, or regular foam. Do NOT get water inside containers. Do NOT use straight streams of water.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Use water spray to dilute spill to a non-flammable mixture. Avoid runoff into storm sewers and ditches which lead to waterways. Wash area with soap and water. Use water spray to disperse the gas/vapor. Provide ventilation. Cover with material such as dry soda ash or calcium carbonate and place into a closed container for disposal. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Use water spray to dilute spill to a non-flammable mixture. Avoid runoff into storm sewers and ditches which lead to waterways. Wash area with soap and water. Use water spray to disperse the gas/vapor. Provide ventilation. Cover with material such as dry soda ash or calcium carbonate and place into a closed container for disposal. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep away from heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Store in a suitable container in a dry area above the substances freezing point. Do not store near alkaline substances.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep away from heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Store in a suitable container in a dry area above the substances freezing point. Do not store near alkaline substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 64-19-7: United States OSHA: 10 ppm TWA; 25 mg/m3 TWA Belgium - TWA: 10 ppm VLE; 25 mg/m3 VLE Belgium - STEL: 15 ppm VLE; 38 mg/m3 VLE France - VLE: 10 ppm VLE; 25 mg/m3 VLE Germany: 10 ppm TWA; 25 mg/m3 TWA Japan: 10 ppm OEL; 25 mg/m3 OEL Malaysia: 10 ppm TWA; 25 mg/m3 TWA Netherlands: 10 ppm MAC; 25 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 10 ppm VLA-ED; 25 mg/m3 VLA-ED Spain: 15 ppm VLA-EC; 37 mg/m3 VLA-EC CAS# 127-09-3: CAS# 6131-90-4: CAS# 7732-18-5: CAS# 9002-93-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 64-19-7: United States OSHA: 10 ppm TWA; 25 mg/m3 TWA Belgium - TWA: 10 ppm VLE; 25 mg/m3 VLE Belgium - STEL: 15 ppm VLE; 38 mg/m3 VLE France - VLE: 10 ppm VLE; 25 mg/m3 VLE Germany: 10 ppm TWA; 25 mg/m3 TWA Japan: 10 ppm OEL; 25 mg/m3 OEL Malaysia: 10 ppm TWA; 25 mg/m3 TWA Netherlands: 10 ppm MAC; 25 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 10 ppm VLA-ED; 25 mg/m3 VLA-ED Spain: 15 ppm VLA-EC; 37 mg/m3 VLA-EC CAS# 127-09-3: CAS# 6131-90-4: CAS# 7732-18-5: CAS# 9002-93-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Acetaldehyde, 2-aminoethanol, ammonium nitrate, bromine pentafluoride, chlorine trifluoride, chlorosulfonic acid, chromic acid anhydride, acetic anhydride, diallyl methyl carbinol + ozone, ethylene diamine, ethyleneimine, hydrogen peroxides, nitric acid, nitric acid + acetone, oleum, perchloric acid, permanganates, phosphorus isocyanate, phosphorus trichloride, potassium hydroxide, potassium-tert-butoxide, sodium hydroxide, sodium peroxide, xylene, metals, acid anhydrides, peroxides, amines, alcohols, calcium salts, sodium salts, Attacks some forms of plastics, rubbers, and coatings., chromium trioxide, chromic anhydride, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), carbonates, strong oxidizing agents, strong reducing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Acetaldehyde, 2-aminoethanol, ammonium nitrate, bromine pentafluoride, chlorine trifluoride, chlorosulfonic acid, chromic acid anhydride, acetic anhydride, diallyl methyl carbinol + ozone, ethylene diamine, ethyleneimine, hydrogen peroxides, nitric acid, nitric acid + acetone, oleum, perchloric acid, permanganates, phosphorus isocyanate, phosphorus trichloride, potassium hydroxide, potassium-tert-butoxide, sodium hydroxide, sodium peroxide, xylene, metals, acid anhydrides, peroxides, amines, alcohols, calcium salts, sodium salts, Attacks some forms of plastics, rubbers, and coatings., chromium trioxide, chromic anhydride, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), carbonates, strong oxidizing agents, strong reducing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 64-19-7: AF1225000 CAS# 127-09-3: AJ4300010 CAS# 6131-90-4: AJ4580000 CAS# 7732-18-5: ZC0110000 CAS# 9002-93-1: MD0907700 YM0616666 YM0683332 LD50/LC50:
CAS# 64-19-7: Draize test, rabbit, skin: 50 mg/24H Mild; Inhalation, mouse: LC50 = 5620 ppm/1H; Oral, rat: LD50 = 3310 mg/kg; Skin, rabbit: LD50 = 1060 uL/kg.
CAS# 127-09-3: Draize test, rabbit, eye: 10 mg Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >30 gm/m3/1H; Oral, mouse: LD50 = 6891 mg/kg; Oral, rat: LD50 = 3530 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
CAS# 6131-90-4.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 9002-93-1: Draize test, rabbit, eye: 10 uL/24H Moderate; Draize test, rabbit, skin: 500 uL/24H Mild; Oral, rat: LD50 = 1800 mg/kg; Oral, rat: LD50 = 3800 mg/kg; Oral, rat: LD50 = 1900 mg/kg.
Carcinogenicity:
Acetic acid - Not listed by ACGIH, IARC, or NTP.
Sodium acetate - Not listed by ACGIH, IARC, or NTP.
Acetate, sodium, trihydrate - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Ethoxylated p-tert-octylphenol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 64-19-7: AF1225000 CAS# 127-09-3: AJ4300010 CAS# 6131-90-4: AJ4580000 CAS# 7732-18-5: ZC0110000 CAS# 9002-93-1: MD0907700 YM0616666 YM0683332 LD50/LC50:
CAS# 64-19-7: Draize test, rabbit, skin: 50 mg/24H Mild; Inhalation, mouse: LC50 = 5620 ppm/1H; Oral, rat: LD50 = 3310 mg/kg; Skin, rabbit: LD50 = 1060 uL/kg.
CAS# 127-09-3: Draize test, rabbit, eye: 10 mg Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >30 gm/m3/1H; Oral, mouse: LD50 = 6891 mg/kg; Oral, rat: LD50 = 3530 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
CAS# 6131-90-4.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 9002-93-1: Draize test, rabbit, eye: 10 uL/24H Moderate; Draize test, rabbit, skin: 500 uL/24H Mild; Oral, rat: LD50 = 1800 mg/kg; Oral, rat: LD50 = 3800 mg/kg; Oral, rat: LD50 = 1900 mg/kg.
Carcinogenicity:
Acetic acid - Not listed by ACGIH, IARC, or NTP.
Sodium acetate - Not listed by ACGIH, IARC, or NTP.
Acetate, sodium, trihydrate - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Ethoxylated p-tert-octylphenol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Bluegill/Sunfish: LC50 = 75 mg/L; 96 Hr; CAS# 64-19-7: UnspecifiedFish: Goldfish: LC50 = 423 mg/L; 24 Hr; CAS# 64-19-7: UnspecifiedWater flea Daphnia: EC50 = 32-47 mg/L; 24-48 Hr; CAS# 64-19-7: UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 8.86-11 mg/L; 5,15,25 min; CAS# 64-19-7: Microtox testFish: Fathead Minnow: LC50 = 88 mg/L; 96 Hr; CAS# 64-19-7: Static bioassay @ 18-22CFish: Bluegill/Sunfish: LC50 = 75 mg/L; 96 Hr; CAS# 64-19-7: UnspecifiedFish: Goldfish: LC50 = 423 mg/L; 24 Hr; CAS# 64-19-7: UnspecifiedWater flea Daphnia: EC50 = 32-47 mg/L; 24-48 Hr; CAS# 64-19-7: UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 =
Fish: Bluegill/Sunfish: LC50 = 75 mg/L; 96 Hr; CAS# 64-19-7: UnspecifiedFish: Goldfish: LC50 = 423 mg/L; 24 Hr; CAS# 64-19-7: UnspecifiedWater flea Daphnia: EC50 = 32-47 mg/L; 24-48 Hr; CAS# 64-19-7: UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 8.86-11 mg/L; 5,15,25 min; CAS# 64-19-7: Microtox testFish: Fathead Minnow: LC50 = 88 mg/L; 96 Hr; CAS# 64-19-7: Static bioassay @ 18-22CFish: Bluegill/Sunfish: LC50 = 75 mg/L; 96 Hr; CAS# 64-19-7: UnspecifiedFish: Goldfish: LC50 = 423 mg/L; 24 Hr; CAS# 64-19-7: UnspecifiedWater flea Daphnia: EC50 = 32-47 mg/L; 24-48 Hr; CAS# 64-19-7: UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 =
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ACETIC ACID SOLUTION
Hazard Class: 8
UN Number: 2790
Packing Group: II
IMO
Shipping Name: ACETIC ACID SOLUTION
Hazard Class: 8
UN Number: 2790
Packing Group: II
RID/ADR
Shipping Name: ACETIC ACID SOLUTION
Hazard Class: 8
UN Number: 2790
Packing group: II
USA RQ: CAS# 64-19-7: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 35 Causes severe burns.
Safety Phrases:
S 2 Keep out of reach of children.
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 64-19-7: 1
CAS# 127-09-3: 1
CAS# 6131-90-4: 1
CAS# 7732-18-5: No information available.
CAS# 9002-93-1: 1
Canada
CAS# 64-19-7 is listed on Canadas DSL List.
CAS# 127-09-3 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 9002-93-1 is listed on Canadas DSL List.
CAS# 64-19-7 is listed on Canadas Ingredient Disclosure List.
CAS# 127-09-3 is not listed on Canadas Ingredient Disclosure List.
CAS# 6131-90-4 is not listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 9002-93-1 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 64-19-7 is listed on the TSCA inventory.
CAS# 127-09-3 is listed on the TSCA inventory.
CAS# 6131-90-4 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 9002-93-1 is listed on the TSCA inventory.
