Name:
Sodium fluoride
Synonym:
None
CAS:
7681-49-4
Section 1 - Chemical Product
MSDS Name:Sodium fluoride
Synonym:None
Synonym:None
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 7681-49-4 | Sodium fluoride | >97 | 231-667-8 |
| Hazard Symbols: T Risk Phrases: 25 32 36/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic if swallowed. Contact with acids liberates very toxic gas.
Irritating to eyes and skin.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye irritation and possible burns. May cause chemical conjunctivitis and corneal damage.
Skin:
Contact with skin causes irritation and possible burns, especially if the skin is wet or moist. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
Ingestion of large amounts of fluoride may cause salivation, nausea, vomiting, abdominal pain, fever, labored breathing. Exposure to fluoride compounds can result in systemic toxic effects on the heart, liver, and kidneys. It may also deplete calcium levels in the body leading to hypocalcemia and death. May cause irritation of the digestive tract and possible burns. May cause respiratory paralysis and cardiac arrest.
Inhalation:
May cause severe irritation of the respiratory tract with possible burns. Aspiration may lead to pulmonary edema. Prolonged exposure to dusts, vapors, or mists may result in the perforation of the nasal septum. May cause systemic effects.
Chronic:
Chronic inhalation and ingestion may cause chronic fluoride poisoning (fluorosis) characterized by weight loss, weakness, anemia, brittle bones, and stiff joints. May cause reproductive and fetal effects. Effects may be delayed. Chronic exposure may cause lung damage. Laboratory experiments have resulted in mutagenic effects. Chronic exposure to fluoride compounds may cause systemic toxicity. Skeletal effects may include bone brittleness, joint stiffness, teeth discoloration, tendon calcification, and osterosclerosis. Animal studies have reported the development of tumors.
Toxic if swallowed. Contact with acids liberates very toxic gas.
Irritating to eyes and skin.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye irritation and possible burns. May cause chemical conjunctivitis and corneal damage.
Skin:
Contact with skin causes irritation and possible burns, especially if the skin is wet or moist. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
Ingestion of large amounts of fluoride may cause salivation, nausea, vomiting, abdominal pain, fever, labored breathing. Exposure to fluoride compounds can result in systemic toxic effects on the heart, liver, and kidneys. It may also deplete calcium levels in the body leading to hypocalcemia and death. May cause irritation of the digestive tract and possible burns. May cause respiratory paralysis and cardiac arrest.
Inhalation:
May cause severe irritation of the respiratory tract with possible burns. Aspiration may lead to pulmonary edema. Prolonged exposure to dusts, vapors, or mists may result in the perforation of the nasal septum. May cause systemic effects.
Chronic:
Chronic inhalation and ingestion may cause chronic fluoride poisoning (fluorosis) characterized by weight loss, weakness, anemia, brittle bones, and stiff joints. May cause reproductive and fetal effects. Effects may be delayed. Chronic exposure may cause lung damage. Laboratory experiments have resulted in mutagenic effects. Chronic exposure to fluoride compounds may cause systemic toxicity. Skeletal effects may include bone brittleness, joint stiffness, teeth discoloration, tendon calcification, and osterosclerosis. Animal studies have reported the development of tumors.
Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Individuals who suffer from diabetes insipidus or some form of renal impairment may be at increased risk from the effects of fluoride. Due to delayed and persistent symptoms, observe patient closely for 48 hours. Treat symptomatically and supportively.
Antidote: None reported.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Individuals who suffer from diabetes insipidus or some form of renal impairment may be at increased risk from the effects of fluoride. Due to delayed and persistent symptoms, observe patient closely for 48 hours. Treat symptomatically and supportively.
Antidote: None reported.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Material will not burn. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Do NOT get water inside containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Material will not burn. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Do NOT get water inside containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Do not flush into a sewer. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Do not flush into a sewer. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Discard contaminated shoes. Keep from contact with moist air and steam.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. Store protected from moisture. Store away from alkalies.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Do not allow contact with water. Discard contaminated shoes. Keep from contact with moist air and steam.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. Store protected from moisture. Store away from alkalies.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7681-49-4: United Kingdom, WEL - TWA: (listed as fluorides, inorganic): 2.5 mg/m3 TWA (as F) United Kingdom, WEL - STEL: (listed as fluorides, inorganic): 6.2 mg/m3 STEL (as F) United States OSHA: 2.5 mg/m3 TWA (as F) (listed under Fluorides).2.5 mg/m3 TWA (as F) (listed under Fluorides).
Belgium - TWA: (listed as fluorides, inorganic): 2.5 mg/m3 VLE (a France - VME: 2 mg/m3 VME (as F) Germany: (listed as fluorides): 2.5 mg/m3 VME (as F) Malaysia: (listed as fluorides): 2.5 mg/m3 TWA (as F) Netherlands: (listed as fluorides): 3.5 mg/m3 STEL (as F) Russia: 1 mg/m3 TWA Russia: 0.2 mg/m3 STEL Spain: (listed as fluorides, inorganic): 2.5 mg/m3 VLA-ED (except uranium hexafluoride, as F) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7681-49-4: United Kingdom, WEL - TWA: (listed as fluorides, inorganic): 2.5 mg/m3 TWA (as F) United Kingdom, WEL - STEL: (listed as fluorides, inorganic): 6.2 mg/m3 STEL (as F) United States OSHA: 2.5 mg/m3 TWA (as F) (listed under Fluorides).2.5 mg/m3 TWA (as F) (listed under Fluorides).
Belgium - TWA: (listed as fluorides, inorganic): 2.5 mg/m3 VLE (a France - VME: 2 mg/m3 VME (as F) Germany: (listed as fluorides): 2.5 mg/m3 VME (as F) Malaysia: (listed as fluorides): 2.5 mg/m3 TWA (as F) Netherlands: (listed as fluorides): 3.5 mg/m3 STEL (as F) Russia: 1 mg/m3 TWA Russia: 0.2 mg/m3 STEL Spain: (listed as fluorides, inorganic): 2.5 mg/m3 VLA-ED (except uranium hexafluoride, as F) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystalline powder
Color: white to off-white
Odor: odorless
pH: 7.4 (solution)
Vapor Pressure: 1 mm Hg @ 1077 deg C
Viscosity: Not available.
Boiling Point: 1704 deg C
Freezing/Melting Point: 993 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble.
Specific Gravity/Density: 2.78 (water=1)
Molecular Formula: NaF
Molecular Weight: 41.9882
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Moisture sensitive.
Conditions to Avoid:
Incompatible materials, dust generation, moisture, excess heat.
Incompatibilities with Other Materials:
Moisture, acids, alkalies, glass, oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, hydrogen fluoride gas, sodium oxide.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures. Moisture sensitive.
Conditions to Avoid:
Incompatible materials, dust generation, moisture, excess heat.
Incompatibilities with Other Materials:
Moisture, acids, alkalies, glass, oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, hydrogen fluoride gas, sodium oxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7681-49-4: WB0350000 LD50/LC50:
CAS# 7681-49-4: Draize test, rabbit, eye: 20 mg/24H Moderate; Oral, mouse: LD50 = 44 mg/kg; Oral, rabbit: LD50 = 200 mg/kg; Oral, rat: LD50 = 31 mg/kg.
Carcinogenicity:
Sodium fluoride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 7681-49-4: WB0350000 LD50/LC50:
CAS# 7681-49-4: Draize test, rabbit, eye: 20 mg/24H Moderate; Oral, mouse: LD50 = 44 mg/kg; Oral, rabbit: LD50 = 200 mg/kg; Oral, rat: LD50 = 31 mg/kg.
Carcinogenicity:
Sodium fluoride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Mosquito Fish: TLm = 419 ppm; 96 Hr; Fresh waterWater flea Daphnia: LC50 = 340 mg/L; 48 Hr; Unspecified Other Dangerous to aquatic life in high concentrations.
Fish: Mosquito Fish: TLm = 419 ppm; 96 Hr; Fresh waterWater flea Daphnia: LC50 = 340 mg/L; 48 Hr; Unspecified Other Dangerous to aquatic life in high concentrations.
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: SODIUM FLUORIDE
Hazard Class: 6.1
UN Number: 1690
Packing Group: III
IMO
Shipping Name: SODIUM FLUORIDE, SOLID
Hazard Class: 6.1
UN Number: 1690
Packing Group: III
RID/ADR
Shipping Name: SODIUM FLUORIDE
Hazard Class: 6.1
UN Number: 1690
Packing group: III
USA RQ: CAS# 7681-49-4: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 25 Toxic if swallowed.
R 32 Contact with acids liberates very toxic gas.
R 36/38 Irritating to eyes and skin.
Safety Phrases:
S 22 Do not breathe dust.
S 36 Wear suitable protective clothing.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 7681-49-4: 1
Canada
CAS# 7681-49-4 is listed on Canadas DSL List.
CAS# 7681-49-4 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7681-49-4 is listed on the TSCA inventory.
