Name:
Sodium tri-sec-butylborohydride 1M solution in tetrahydrofuran
Synonym:
Sodium hydrotri-sec-butylborate(1-) in THF
CAS:
109-99-9
Section 1 - Chemical Product
MSDS Name:Sodium tri-sec-butylborohydride 1M solution in tetrahydrofuran
Synonym:Sodium hydrotri-sec-butylborate(1-) in THF
Synonym:Sodium hydrotri-sec-butylborate(1-) in THF
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 109-99-9 | Tetrahydrofuran | 80 | 203-726-8 |
| Hazard Symbols: F C Risk Phrases: 11 15 19 34 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Contact with water liberates extremely flammable gases. May form explosive peroxides. Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns. May be absorbed through the skin. If absorbed, causes symptoms similar to those of inhalation.
Ingestion:
Causes gastrointestinal tract burns. May cause central nervous system depression.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
May cause liver and kidney damage. May cause lung damage. Narcotic in high concentrations.
Highly flammable. Contact with water liberates extremely flammable gases. May form explosive peroxides. Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns. May be absorbed through the skin. If absorbed, causes symptoms similar to those of inhalation.
Ingestion:
Causes gastrointestinal tract burns. May cause central nervous system depression.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
May cause liver and kidney damage. May cause lung damage. Narcotic in high concentrations.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Forms peroxides of unknown stability. Contact with water liberates highly flammable gases. Extremely flammable liquid and vapor. Vapor may cause flash fire. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Do NOT use water directly on fire. Use dry chemical to fight fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Forms peroxides of unknown stability. Contact with water liberates highly flammable gases. Extremely flammable liquid and vapor. Vapor may cause flash fire. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Do NOT use water directly on fire. Use dry chemical to fight fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Isolate area and deny entry. Provide ventilation. Do not expose spill to water.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Isolate area and deny entry. Provide ventilation. Do not expose spill to water.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Do not allow contact with water. Prevent build up of vapors to explosive concentration. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Keep under a nitrogen blanket.
Water free area. Containers should be dated when opened and tested periodically for the presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Do not allow contact with water. Prevent build up of vapors to explosive concentration. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Keep under a nitrogen blanket.
Water free area. Containers should be dated when opened and tested periodically for the presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 67276-04-4: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 67276-04-4: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: ether-like
pH: Not available.
Vapor Pressure: 145 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 66 deg C
Freezing/Melting Point: -108.5 deg C
Autoignition Temperature: 321 deg C ( 609.80 deg F)
Flash Point: -15 deg C ( 5.00 deg F)
Explosion Limits, lower: 2.0 vol%
Explosion Limits, upper: 11.8 vol%
Decomposition Temperature:
Solubility in water: Reacts.
Specific Gravity/Density: .890 g/ml
Molecular Formula: C12H28BNa
Molecular Weight: 206.15
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation. THF should never be distilled to dryness.
Conditions to Avoid:
Light, ignition sources, exposure to air, contact with water, excess heat, evaporating to near dryness, confined spaces.
Incompatibilities with Other Materials:
Water, strong oxidizing agents, strong acids, alcohols, oxygen, bromine, alkali hydroxides, metal halides.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, oxides of boron, borane, hydrogen gas, sodium oxide.
Hazardous Polymerization: May occur.
Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation. THF should never be distilled to dryness.
Conditions to Avoid:
Light, ignition sources, exposure to air, contact with water, excess heat, evaporating to near dryness, confined spaces.
Incompatibilities with Other Materials:
Water, strong oxidizing agents, strong acids, alcohols, oxygen, bromine, alkali hydroxides, metal halides.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, oxides of boron, borane, hydrogen gas, sodium oxide.
Hazardous Polymerization: May occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 109-99-9: LU5950000 CAS# 67276-04-4 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 67276-04-4.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Sodium tri-sec-butylborohydride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 109-99-9: LU5950000 CAS# 67276-04-4 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 67276-04-4.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Sodium tri-sec-butylborohydride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: WATER-REACTIVE LIQUID, CORROSIVE, N.O.S.*
Hazard Class: 4.3 (8)
UN Number: 3129
Packing Group: II
IMO
Shipping Name: WATER-REACTIVE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 4.3 (8)
UN Number: 3129
Packing Group: II
RID/ADR
Shipping Name: WATER-REACTIVE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 4.3 (8)
UN Number: 3129
Packing group: II
USA RQ: CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 15 Contact with water liberates extremely
flammable gases.
R 19 May form explosive peroxides.
R 34 Causes burns.
Safety Phrases:
S 7/8 Keep container tightly closed and dry.
S 16 Keep away from sources of ignition - No
smoking.
S 25 Avoid contact with eyes.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 109-99-9: 1
CAS# 67276-04-4: No information available.
Canada
CAS# 109-99-9 is listed on Canadas DSL List.
CAS# 109-99-9 is listed on Canadas Ingredient Disclosure List.
CAS# 67276-04-4 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 109-99-9 is listed on the TSCA inventory.
CAS# 67276-04-4 is not listed on the TSCA inventory.
It is for research and development use only.
